Cancer Therapeutics: Experimental and Clinical Agents

Author:   Beverly A. Teicher
Publisher:   Humana Press Inc.
Edition:   1997 ed.
ISBN:  

9780896034600


Pages:   451
Publication Date:   03 December 1996
Format:   Hardback
Availability:   In Print   Availability explained
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Cancer Therapeutics: Experimental and Clinical Agents


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Overview

This comprehensive review of existing and potential anticancer drugs and therapies by leading researchers from academia, government laboratories, and pharmaceutical companies offers essential insight into what has been accomplished and where the experimental therapy of cancer is going. The authoritative contributors illuminate the current status of the major molecules of cancer treatment, ranging from the nitrogen mustards through platinum complexes to interferons, cytokines, growth factors and their inhibitors, and on to immunotoxins, antisense oligonucleotides, and gene therapy. A companion volume by the same editor (Anticancer Drug Development Guide: Preclinical and Clinical Screening and Approval) details the processes by which new anticancer drugs are approved. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.

Full Product Details

Author:   Beverly A. Teicher
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1997 ed.
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   1.021kg
ISBN:  

9780896034600


ISBN 10:   0896034607
Pages:   451
Publication Date:   03 December 1996
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

I. Cytotoxic Agents: Old and New.- 1 Nitrogen Mustards.- 2 Phosphoramide and Oxazaphosphorine Mustards.- 3 Development of the Nitrosoureas.- 4 Platinum Complexes.- 5 Anthracyclines.- 6 Topoisomerase I Inhibitors.- 7 DNA Topoisomerase II Inhibitors.- 8 The Taxoids.- 9 Sequence-Selective Groove Binders.- 10 Bis-Naphthalimides: Synthesis and Preclinical Evaluation.- II. Newer Strategies and Targets.- 11 The Enediynes.- 12 Matrix Metalloproteinase Inhibitors.- 13 Interferons and Other Cytokines.- 14 Discovery of TNP-470 and Other Angiogenesis Inhibitors.- 15 Antisense Oligonucleotides.- 16 Growth Factors and Growth Factor Inhibitors.- 17 Immunoconjugates.- 18 A Case for ras Targeted Agents as Antineoplastics.- 19 Gene Therapy.

Reviews

"...extremely readable...excellent treatment of drugs such as naphthalimides... Each chapter is succinct and well-written."-Cancer Forum"...a most important source of literature for all those who are involved in basic cancer research and in the clinical care of cancer patients in different fields of medicine."-Haematologia


...extremely readable...excellent treatment of drugs such as naphthalimides...Each chapter is succinct and well-written. -Cancer Forum ...a most important source of literature for all those who are involved in basic cancer research and in the clinical care of cancer patients in different fields of medicine. -Haematologia


...extremely readable...excellent treatment of drugs such as naphthalimides...Each chapter is succinct and well-written. -Cancer Forum ...a most important source of literature for all those who are involved in basic cancer research and in the clinical care of cancer patients in different fields of medicine. -Haematologia


...extremely readable...excellent treatment of drugs such as naphthalimides...Each chapter is succinct and well-written. -Cancer Forum ...a most important source of literature for all those who are involved in basic cancer research and in the clinical care of cancer patients in different fields of medicine. -Haematologia


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