Overview

The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.

Full Product Details

Author:   Sadegh Babashah
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
Weight:   1.202kg
ISBN:  

9783319363936

ISBN 10:   331936393
Pages:   560
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface Part I. The Biology of Cancer Stem Cells Chapter 1 Cancer Stem Cells: A Quick Walk through the Concepts Katayoon Pakravan, Mohammad Amin Mahjoub, Sadegh Babashah   Chapter 2 Cellular Plasticity, Cancer Stem Cells and Metastasis Paola Ferrari, Andrea Nicolini   Chapter 3 Cytokine Networks and Cancer Stem Cells Clifford Liongue, Alister C Ward, Wei Duan, Sarah Shigdar   Chapter 4 Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression Claudia Peitzsch, Monica Cojoc, Ina Kurth, Anna Dubrovska Chapter 5 Non-coding RNAs in Cancer and Cancer Stem Cells Ryou-u Takahashi, Hiroaki Miyazaki, Takahiro Ochiya Chapter 6 Self-renewal Pathways in Mammary Stem Cells and Carcinogenesis Lu Deng, Jiahui Xu, Dong Wang, Suling Liu Part II. Cancer Stem Cells in Human Malignancies Chapter 7 Breast Cancer Stem Cells Giorgia G. Silveira, Joao Paulo Oliveira-Costa, Alfredo Ribeiro-Silva Chapter 8 Lung Cancer Stem Cells Gavitt A. Woodard, David M. Jablons   Chapter 9 Colorectal Cancer Stem Cells Pratima Nangia-Makker, Yingjie Yu, Lulu Farhana, Kulsoom Ahmed, Adhip P.N. Majumdar Chapter 10 Pancreatic Cancer Stem Cells Deepak Ray, Reyhaneh Khoshchehreh, Alexandra Aicher, Christopher Heeschen Chapter 11  Glioblastoma Cancer Stem Cells Luca Persano,  Alessandro Della Puppa,  Elena Porcù,  Francesca Maule,  Giampietro Viola Chapter 12 Head and Neck Cancer Stem Cells Chiara Bianchini, Andrea Ciorba Chapter 13 Leukemic and Lymphoid Stem Cells Michael W. Becker, Kristen M. O’Dwyer   Chapter 14 Leukemic Stem Cells in Acute Lymphoblastic Leukemia Ugo Testa   Part III. Novel Approaches for Targeting Cancer Stem Cells Chapter 15 Targeting Key Stemness-Related Pathways in Human Cancers Kyrsta M Coyle, Margaret L Thomas, Mohammad Sultan, Paola Marcato   Chapter 16 Targeting Cancer Stem Cells and the Tumor Microenvironment Alice Turdo, Matilde Todaro, Giorgio Stassi   Chapter 17 Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance Margaret L Thomas, Krysta M Coyle, Mohammad Sultan, Paola Marcato   Chapter 18 Cancer Stem Cells and Tumor Radioresistance Aadel A Chaudhuri, Michael S Binkley, Maximilian Diehn   Chapter 19 Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies Chunguang Yang, Kunlin Jin, Yue Zhang, Hong Sun, William C Cho    Index

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