Overview

A collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.

Full Product Details

Author:   John Swansbury
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2003 ed.
Volume:   220
Dimensions:   Width: 15.20cm , Height: 1.70cm , Length: 22.90cm
Weight:   0.428kg
ISBN:  

9781617373442

ISBN 10:   1617373443
Pages:   296
Publication Date:   09 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Introduction John Swansbury Cytogenetic Studies in Hematologic Malignancies: An Overview John Swansbury The Myeloid Disorders: Background John Swansbury Cytogenetic Techniques for Myeloid Disorders John Swansbury Acute Lymphoblastic Leukemia: Background John Swansbury Conventional Cytogenetic Techniques in the Diagnosis of Childhood Acute Lymphoblastic Leukemia Susana C. Raimondi and Susan Mathew Chromosome Preparations from Bone Marrow in Acute Lymphoblastic Leukemia: Cytogenetic Techniques Ann Watmore Lymphoid Disorders Other than Common Acute Lymphoblastic Leukemia: Background John Swansbury Other Lymphoid Malignancies: Cytogenetic Techniques John Swansbury Cytogenetic and Genetic Studies in Solid Tumors: Background John Swansbury Human Solid Tumors: Cytogenetic Techniques Pietro Polito, Paola Dal Cin, Maria Debiec-Rychter, and Anne Hagemeijer Analysis and Interpretation of Cytogenetic Findings in Malignancies John Swansbury Cytogenetic Studies Using FISH: Background Toon Min and John Swansbury FISH Techniques Toon Min FISH, CGH, and SKY in the Diagnosis of Childhood Acute Lymphoblastic Leukemia Susan Mathew and Susana C. Raimondi Solving Problems in Multiplex FISH Jon C. Strefford Some Difficult Choices in Cytogenetics John Swansbury Introduction to the Analysis of the Human G-Banded Karyotype John Swansbury Index About the Authors

Reviews

Eminently practical for every stage of diagnostic service, this book offers laboratories a user-friendly collection of standard and advanced techniques, carefully designed to improve diagnosis and clinical management of cancer patients. - Clinical Laboratory International ...an immensely useful book for anyone working in the field of cytogenetics. The author has filled this volume with the sort of detail that enables ready translation of methods into practice and provides clear explanations of individual steps within procedures... - Cancer Forum

"""Eminently practical for every stage of diagnostic service, this book offers laboratories a user-friendly collection of standard and advanced techniques, carefully designed to improve diagnosis and clinical management of cancer patients."" - Clinical Laboratory International ""...an immensely useful book for anyone working in the field of cytogenetics. The author has filled this volume with the sort of detail that enables ready translation of methods into practice and provides clear explanations of individual steps within procedures..."" - Cancer Forum"

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