Overview

Neurons in the brain communicate with each other by transmitting sequences of electrical spikes or action potentials. One of the major challenges in neuroscience is to understand the basic physiological mechanisms underlying the complex spatiotemporal patterns of spiking activity observed during normal brain functioning, and to determine the origins of pathological dynamical states such as epileptic seizures and Parkinsonian tremors. A second major challenge is to understand how the patterns of spiking activity provide a substrate for the encoding and transmission of information, that is, how do neurons compute with spikes? It is likely that an important element of both the dynamical and computational properties of neurons is that they can exhibit bursting, which is a relatively slow rhythmic alternation between an active phase of rapid spiking and a quiescent phase without spiking. This book provides a detailed overview of the current state-of-the-art in the mathematical and computational modeling of bursting, with contributions from many of the leading researchers in the field.

Full Product Details

Author:   Steve Coombes (Univ Of Nottingham & Loughborogh Univ, Uk) ,  Paul Bressloff (Univ Of Utah, Usa)
Publisher:   World Scientific Publishing Co Pte Ltd
Imprint:   World Scientific Publishing Co Pte Ltd
Dimensions:   Width: 15.60cm , Height: 2.70cm , Length: 23.50cm
Weight:   0.680kg
ISBN:  

9789812565068

ISBN 10:   981256506
Pages:   420
Publication Date:   04 October 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

Table of Contents

# Bursting at the Single Cell Level: # The Development of the Hindmarshrose Model for Bursting (J Hindmarsh & P Cornelius) # Negative Calcium Feedback: The Road from Chay-Keizer (R Bertram & A Sherman) # Autoregulation of Bursting of AVP Neurons of the Rat Hypothalamus (P Roper et al.) # Bifurcations in the Fast Dynamics of Neurons: Implications for Bursting (J Guckenheimer et al.) # Bursting in 2-Compartment Neurons: A Case Study of the Pinsky-Rinzel Model (A Bose & V Booth) # Ghostbursting: The Role of Active Dendrites in Electrosensory Processing (C R Laing & B Doiron) # Bursting at the Network Level: # Analysis of Circuits Containing Bursting Neurons Using Phase Resetting Curves (C Canavier) # Bursting in Coupled Cell Systems (M Golubitsky et al.) # Modulatory Effects of Coupling on Bursting Maps (G de Vries) # Beyond Synchronization: Modulatory and Emergent Effects of Coupling in Square-Wave Bursting (G de Vries & A Sherman) # Bursting in Excitatory Neural Networks (J Tabak & J Rinzel) # Oscillatory Bursting Mechanisms in Respiratory Pacemaker Neurons and Networks (R Butera et al.) # Geometric Analysis of Bursting Networks (J Best & D Terman) # Elliptic Bursters, Depolarization Block, and Waves (B Ermentrout et al.)

Reviews

""All of the chapters are clearly written and for the most part would be accessible to readers who have taken at least an undergraduate course that covers modeling of neuronal dynamics ... The excitement generated by this collection of papers stems from the demonstration that appropriate interdisciplinary teams are indeed forming to tackle the outstanding issues.""Mathematical Reviews

All of the chapters are clearly written and for the most part would be accessible to readers who have taken at least an undergraduate course that covers modeling of neuronal dynamics ... The excitement generated by this collection of papers stems from the demonstration that appropriate interdisciplinary teams are indeed forming to tackle the outstanding issues. Mathematical Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions