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OverviewThis is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist. Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable. All of these emerging issues are extensively discussed in this book, and practical evidence-based treatment recommendations are presented whenever possible. Full Product DetailsAuthor: Jonathan Strauss , William Small , Gayle E. WoloschakPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Dimensions: Width: 21.00cm , Height: 1.00cm , Length: 27.90cm Weight: 0.489kg ISBN: 9783642312199ISBN 10: 3642312195 Pages: 90 Publication Date: 02 June 2015 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsBiological subtypes of breast cancer.- Oncogene amplification and Herceptin.- Current clinical use of genetic profiling.- Biology of DCIS and progression to invasive disease.- Cancer Stem Cells and Radiotherapy.- Genetic basis of normal tissue radiosensitivity and late toxicity.- Genetic syndromes and radiotherapy in breast cancer.- Experimental therapies in breast cancer.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |