Full Product Details
Author: Jacques Fantini (Molecular Interactions in Model and Biological Membranes Laboratory, Faculty of Science and Technology, Marseille, France) ,
Nouara Yahi (Molecular Interactions in Model and Biological Membranes Laboratory, Faculty of Science and Technology, Marseille, France)
Publisher: Elsevier Science Publishing Co Inc
Imprint: Academic Press Inc
Dimensions:
Width: 19.10cm
, Height: 2.30cm
, Length: 23.50cm
Weight: 0.950kg
ISBN: 9780128001110
ISBN 10: 0128001119
Pages: 398
Publication Date: 03 July 2015
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Author Information
Jacques Fantini was born in France in 1960. He has over 30 years of teaching and research experience in biochemistry and neurochemistry areas. Since 1998, he is professor of biochemistry and honorary member of the ‘Institut Universitaire de France’. He has demonstrated the implication of glycolipids in the attachment and fusion of HIV-1 with the plasma membrane of target cells, and has published several important articles in this field. He is an active member of the research group ‘Molecular Interactions in Model and Biological Membrane Systems’ led by Nouara Yahi. This group is internationally recognized for studies of lipid-lipid and lipid-protein interactions pertaining to virus fusion, amyloid aggregation, oligomerization and pore formation. Together with Nouara Yahi, Jacques Fantini has discovered the universal sphingolipid-binding domain (SBD) in proteins with no sequence homology but sharing common structural features mediating sphingolipid recognition. The SBD is present in a broad range of infectious and amyloid proteins, revealing common mechanisms of pathogenesis in viral and bacterial brain infections, and in neurodegenerative diseases. His current research is focused on the molecular organization of the synapse in physiological and pathological conditions. Jacques Fantini is the author/co-author of 175 articles (PubMed), with 7500 citations and a H-index of 49. He has also published 4 patent applications. Jacques Fantini personal web site: https://jfantini.jimdo.com Nouara Yahi was born in France in 1964. She has accumulated 25 years of fundamental research and teaching experience in virology and molecular biology areas. She has been a pioneer in the analysis of resistance mutations in patients with HIV infections, and has published several important articles in this field. She is currently professor of biochemistry at Aix-Marseille University and leader of the research group ‘Molecular Interactions in Model and Biological Membrane Systems’. This group is internationally recognized for studies of lipid-lipid and lipid-protein interactions pertaining to virus fusion, amyloid aggregation, oligomerization and pore formation. Together with her teammate Jacques Fantini, Nouara Yahi has discovered the universal sphingolipid-binding domain (SBD) in proteins with no sequence homology but sharing common structural features mediating sphingolipid recognition. The SBD is present in a broad range of infectious and amyloid proteins, revealing common mechanisms of pathogenesis in viral and bacterial brain infections, and in neurodegenerative diseases. Nouara Yahi is the author/co-author of 90 articles (PubMed), with 4400 citations and a H-index of 40. She has also published 5 patent applications.
