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OverviewThis book reflects the meteoric increase in knowledge regarding bone remodeling including molecular understanding of osteoclast development, regulatory molecules such as cytokines, pathophysiology and pharmaceutical development to treat osteoclast function. Rapid publication of an up-to-date volume addressing these issues by experts in the field, an asset to any library of clinical endocrinologists and rheumatologists, is a valuable read for those entering the scientific arena of bone remodeling research. It integrates recent technological advances with foundation data to provide a comprehensive view of bone resorption, and also links information gained from the genetic and molecular to the physiological and clinical levels. It is addressed to clinical practitioners, nutrition scientists, researchers and students, who seek a fundamental understanding of this important subject. An invaluable publication for the community of medical specialists- internists, endocrinologists, nephrologists, orthopaedists- as well as dental, paramedical and nursing practitioners. Full Product DetailsAuthor: Felix Bronner , Mary C. Farach-Carson , Janet RubinPublisher: Springer London Ltd Imprint: Springer London Ltd Edition: 2005 ed. Volume: 2 Dimensions: Width: 17.80cm , Height: 1.20cm , Length: 25.40cm Weight: 1.340kg ISBN: 9781852338121ISBN 10: 1852338121 Pages: 190 Publication Date: 08 August 2005 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Out of print, replaced by POD We will order this item for you from a manufatured on demand supplier. Table of ContentsOsteoclast: Origin and Differentiation.- Osteolytic Enzymes of Osteoclasts.- Regulation of Osteoclast Activity.- Structural Aspects of Bone Resorption.- Inflammatory Cytokines.- Genetics and Mutations Affecting Osteoclast Development and Function.- Clinical Disorders Associated with Alterations in Bone Resorption.- Pharmaceuticals for Bone Disease Targeting the Osteoclast.- Skeletal Complications of Malignancy: Central Role for the Osteoclast.ReviewsFrom the reviews: Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists. (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005) From the reviews: Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists. (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005) From the reviews: <p> Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists. (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005) Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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