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Author:   Vassilios Vassiliou ,  Edward Chow ,  Dimitrios Kardamakis
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 2nd ed. 2014
Volume:   21
Dimensions:   Width: 15.50cm , Height: 2.60cm , Length: 23.50cm
Weight:   7.489kg
ISBN:  

9789402405002

ISBN 10:   9402405003
Pages:   490
Publication Date:   17 September 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface. I Fundamental Concepts.- Pathophysiology of metastatic bone disease.- Bone metastases: epidemiology, clinical picture, SREs and prognosis.- Pain in bone metastases: types and mechanisms. II Investigations Of Bone Metastases.- Radiological evaluations: radiography, CT, MRI.- Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT.- Bone turnover markers.- New omics approaches for bone metastases. III Therapeutic Management.- Analgesic treatment for bone mets.- Radiotherapy: external beam and radio-surgery.- Radionuclide therapy.- Bisphosphonates.- New targeted therapies for bone metastases.- Chemotherapy and hormone therapy.- HIFU/Radioablation.- Neuropathic bone metastases.- Spinal cord compression and cauda equina compression.- Pathological and impending fracture.- Re-irradiation.- Bone metastases in elderly patients.- Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV Assesment of Therapeutic Response.- Radiological and nuclear medicine imaging modalities.- Clinical assessment measures.- Outcome measures in bone metastases clinical trials.- Quality of life in patients suffering from metastatic skeletal disease. V Cost of Managing Metastatic Bone Disease.- Cost effectiveness of treatment modalities for bone metastases.- Index.

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