Overview

Plastic containers are increasingly being used for the packaging of pharmaceutical products-solids, powders, liquids, creams and ointments-sterile and non-sterile. No only do plastic containers have proven compatibility with and impermeability to the product itself, but they also have the advantage over glass of being relatively cheap, lightweight, rigid or flexible in shape and shatter resistant. Blow-Fill Seal Technology discusses the advantages of genuine ""in house' packaging manufacture which includes the simultaneous filling and closing of the containers by one machine in one operation, the procedure called BFS, blow-fill-seal or, alternatively, FFS, form-fill-seal technology. This book explains the process in which the BFS machine carries out the complete cycle of blow molding, filling and sealing under conditions in which security can be validated using established aseptic test procedures, offering considerable advantages over conventional aseptic filling of preformed (plastic of other) containers. Offering 61 figures and 21 tables, this book helps people gain a better overview of the types of plastic materials, manufacturing in detail, machinery of BFS technology, validation aspects and quality assurance. Features ·

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