Overview

Significant advances have recently been made towards the widespread use of blood substitutes in clinical practice. These contributions, from experts in the field, discuss areas such as pharmacoeconomics, cancer treatment, improved red cell preservation, polyethylene glycol modification of haemoglobin, and the way in which cell-free oxygen carriers nourish tissues. Each contribution is followed by a transcription of the candid discussions that followed its presentation.

Full Product Details

Author:   R. Winslow ,  Kim D. Vandegriff ,  Marcos Intaglietta
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Edition:   1997 ed.
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.50cm
Weight:   1.500kg
ISBN:  

9780817639808

ISBN 10:   0817639802
Pages:   336
Publication Date:   23 September 1997
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1 Blood Substitutes: 1996 in the Literature.- 2 Blood Substitutes and the Intestinal Microcirculation: Extravasation and Ultrastructural Alterations.- 3 A Discussion of Pharmacoeconomics Applied to Blood Substitutes.- 4 Tumor Microcirculation: Role in Drug and Nutrient Delivery.- 5 The Pressor Effect of Hemoglobin -- Good or Bad?.- 6 Perflubron-based Emulsion: Efficacy as Temporary Oxygen Carrier.- 7 The Other Blood Substitute: Antigenically Inert Erythrocytes.- 8 Hemoglobin Encapsulation With Polyethylene Glycol-modified and Unmodified Vesicles: Systemic and Microvascular Hemodynamics at 80% Blood Substitution.- 9 Hemoglobin Oxygen Affinity and the Design of Red Cell Substitutes.- 10 The Mechanism of Tissue Oxygenation and the Design of Oxygen Carrying Plasma Expanders.- 11 Colloid Osmotic Effects of Hemoglobin-based Oxygen Carriers.- 12 Dextran-Hemoglobin.- 13 Modification of Molecules and Particles With Polyethylene Glycol (PEG): Long-circulating Pharmaceuticals.- 14 The Reaction of Nitric Oxide with Cell-free Hemoglobin Based Oxygen Carriers: Physiological Implications.

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