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Author:   Tatiana Barichello
Publisher:   Springer-Verlag New York Inc.
Imprint:   Humana
Edition:   Second Edition 2025
Volume:   221
ISBN:  

9781071644737

ISBN 10:   1071644734
Pages:   392
Publication Date:   23 May 2025
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

An Overview of the Blood-Brain Barrier.- Differentiation of brain mural cells from human pluripotent stem cell-derived neural crest by activation of Notch3 signaling.- In vitro 2D and 3D cell models of the human blood-brain barrier: demonstrating the beneficial influence of shear stress on brain microvascular endothelial cell phenotype.- Emerging human choroid plexus organoid models for blood–CSF barrier research.- Drosophila as a model to study the blood-brain barrier. -Exploring the use of zebrafish in the blood-brain barrier research.- Evaluation and quantification of blood-brain barrier permeability in a photothrombotic juvenile rodent stroke model using in-vivo MRI and histology.- Transepithelial/transendothelial electrical resistance (TEER) to measure the integrity of blood-brain barrier.- Cell penetrating peptide-decorated nanovectors for nose-to-brain delivery - a new treatment option for CNS diseases.- Microbial Translocation of the Blood-Brain Barrier.- Microdialysis sampling in a free-moving mouse for blood-brain barrier studies.- Methods of Delivering Molecules Through the Blood-Brain Barrier for Brain Diagnostics and Therapeutics.- Transport across the choroid plexus: How to culture choroid plexus epithelial cells and establish a functional assay system.- Increasing BBB Permeability via Focused Ultrasound and Microbubbles: Current Methods in Pre-Clinical Research.- Recording leukocyte rolling and adhesion on meningeal vessels by intravital microscopy.- Molecular Imaging of Blood-Brain Barrier Permeability in Preclinical Models Using PET and SPECT.- Biomarkers for Microvascular Proteins Detection: Blood-Brain Barrier Injury and Damage Measurement (IH, IF, EM, and Quantification of Tight Junction Integrity).- Deep learning and machine learning algorithms: A Blood Brain Barrier Permeability Prediction Model with Accuracy.

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