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Author:   Andy Beaumont (University of Bangor) ,  Pierre Boudry (IFREMER) ,  Kathryn Hoare (University of Bangor)
Publisher:   John Wiley and Sons Ltd
Imprint:   Wiley-Blackwell
Edition:   2nd edition
Dimensions:   Width: 17.80cm , Height: 1.80cm , Length: 25.40cm
Weight:   0.649kg
ISBN:  

9781405188579

ISBN 10:   140518857
Pages:   224
Publication Date:   13 April 2010
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Preface to the second edition ix Acknowledgements xi Chapter 1 What is genetic variation? 1 Deoxyribose nucleic acid 1 Ribose nucleic acid 5 What is the genetic code? 7 Protein structure 7 So what about chromosomes? 9 How does sexual reproduction produce variation? 11 Mitochondrial and chloroplast DNA 16 Chapter 2 How can genetic variation be measured? 19 DNA sequence variation 19 DNA fragment size variation 36 Protein variation 44 Phenotypic variation 47 Chapter 3 Genetic structure in natural populations 49 What is a population? 49 How are allele frequencies estimated? 51 What is the relationship between alleles and genotypes? 51 How do allele frequencies change over time? 53 How does population structure arise? 54 How are genetic markers used to study population structure? 55 Levels of genetic differentiation in aquatic organisms 60 Potential problems with allozymes and coding markers 61 mtDNA variation 63 Microsatellite variation 66 Population structure in the flat oyster 68 Mixed stock analysis (MSA) 73 Chapter 4 Genetics of population size in conservation and aquaculture 77 Genetics of small population size in the wild 78 Genetic markers in conservation 82 Genetics of small population size in the hatchery 85 Is there evidence of loss of genetic variation in the hatchery? 87 How does hatchery propagation affect heterozygosity? 89 Genetic markers for identification of hatchery product 93 Genetic markers for pathogen identification 94 Chapter 5 Genetic variation of traits 99 Qualitative traits 99 Quantitative traits 105 What kinds of traits are important? 106 Variation of a quantitative trait 106 How can we estimate narrow-sense heritability? 109 Realised heritability 115 Correlated traits 118 What types of artificial selections are there? 118 Setting up a breeding programme 122 Inbreeding, cross-breeding and hybridisation 123 Current status of selective breeding programmes in aquaculture 126 Chapter 6 From genetics to genomics 129 What is the genome? 129 Genome mapping 130 Whole genome sequencing: the ‘big picture’ 137 QTL mapping 137 Application of QTLs in aquaculture and fisheries management 138 Marker-assisted selection (MAS): from QTLs to genomic selection 139 Transcriptomics 139 Chapter 7 Triploids and beyond: why manipulate ploidy? 145 How is it done? 146 Production of gynogens and androgens 148 Identification of ploidy change 149 Value of Triploids 151 Tetraploids 155 Gynogens and androgens 157 Chapter 8 Genetic engineering in aquaculture 161 The DNA construct 162 Transgene delivery 164 Transgene integration 168 Detecting integration and expression of the transgene 169 Results of transgenesis efforts in fish 171 So much for transgenics – what about cloning? 176 Genethics 176 Glossary 181 Index 193 Colour plates appear between pages 52 and 53

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Author Information

Andy Beaumont is based at the School of Ocean Sciences, Unioversity of Bangor, Menai, Wales, UK Pierre Boudry, based at IFREMER, France Kate Hoare, based at the School of Ocean Sciences, Menai Bridge, University of Bangor, Wales, UK

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