Overview

Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments. Covering subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.

Full Product Details

Author:   Ivana Pajic-Lijakovic, PhD (Department of Chemical Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Serbia)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443300486

ISBN 10:   0443300488
Pages:   334
Publication Date:   01 May 2026
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Forthcoming
Availability:   Not yet available  
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

Section 1: Tissues self-organisation in morphogenesis 1. Cell adhesion: Common mechanisms and physical principles 2. Analysis of the effect of cell movement on gene expression dynamics in development 3. Force transmission across scales: Examples and measuring methods 4. The impact of air pollution on the tissue self-organisation within co[1]cultured lung systems Section 2: Physics of tissue self-organisation from subcellular to supracellular levels 5. How physical cues guide cell collectives, from local adhesion to global force transmission 6. Cellular death and division events at tissue interfaces: A chicken-or[1]the-egg situation 7. Active Nematics: Exploring the Interplay between structure and dynamics in cell cultures 8. The dynamics along the epithelial-cancer bio-interface within co[1]cultured cell spheroids: Physical aspects 9. Dynamical interplay at the interfaces of cancer cells, immune cells and stromal cells in the extracellular space of artificial model systems and tissues 10. Techniques development to quantify cell-scale dynamic mechanical interactions in extracellular matrices of tissues Section 3: Modeling of the tissue self[1]organization 11. Mathematical modelling approaches to collective cell movement: Leader vs. follower cells Section 4: Engineering of human tissues 12. Engineering of human tissues 13. Conclusion and outlook

Reviews

Author Information

Dr. Ivana Pajic-Lijakovic is a scientific advisor at the Department of Chemical Engineering, University of Belgrade, Serbia. Her research interest is related to biological physics, biorheology and biomechanics. She has previously worked as a guest editor for various special issues and has published a book with Elsevier titled: ‘’Viscoelasticity and Collective Cell Migration: An Interdisciplinary Perspective Across Levels of Organization” (2021). Her research has been published in multiple leading international peer-reviewed journals.

Tab Content 6

Author Website:  

Countries Available

All regions