Overview

Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce.

Full Product Details

Author:   Rakesh Kumar Tekade, PhD (Assistant Professor, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research Ahmedabad, Gujarat, India)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   1.770kg
ISBN:  

9780128144251

ISBN 10:   0128144254
Pages:   752
Publication Date:   08 July 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Routes of administrations and implication on drug bioavailability 2. Biopharmaceutics and Pharmacokinetics considerations in drug research 3. Bioavailability and bioequivalence research in Product Development 4. Pharmacokinetic characterization of drugs and new product designing 5. Pharmacokinetic Modulation with Particulate Drug Formulations 6. Dose, Dosage regimen and Dose adjustment 7. Implications of Bio-Nanotechnology in neuroscience, tissue engineering and cancer therapy 8. Physiologic pharmacokinetics models: Application and limitations 9. Chronopharmacokinetics in drug design 10. Drug toxicity and forensic pharmacokinetics 11. Recent advancements in Pharmacogenomics 12. Biocompatibility testing of biomaterials and biologicals 13. Metabolic kinetics 14. Animal handling and ethical considerations 15. Biopharmaceutic and pharmacokinetic aspects of controlled release systems 16. Degradation of biomaterials in biological environment 17. Safety and long-term toxicity evaluation of polymers used in Pharmaceutical Product Development: Regulatory considerations 18. Toxicity and toxicokinetic consideration in product development and drug research 19. Environmental and safety aspects of bio-nanotechnology 20. Toxicity considerations on repetitive accumulation of polymeric materials

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Author Information

Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.

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