Overview

Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues. This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research.; The key features include: provides up-to-date review of electron microprobe analysis; presents detailed descriptions of sample preparation techniques; covers recent technologies including confocal microscopy, infrared microspectroscopy, and laser raman spectroscopy; features over 100 illustrations with numerous specific applications; contains contributions by world-renowned experts in the field; and, includes a brief summary of highlights which precedes each chapter.

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9786611023294

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