Biomedical Applications of Lanthanum
Author:   Harriet Nilsson ,  Anca Dragomir ,  Godfried M Roomans
Publisher:   Nova Science Publishers Inc
ISBN:  

9781617289064


Pages:   61
Publication Date:   08 March 2011
Format:   Paperback
Availability:   Available To Order   Availability explained
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Biomedical Applications of Lanthanum


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Overview

Lanthanum has been used as a tracer to study tight junctions in epithelia by transmission electron microscopy. The key function of the tight junction complex (TJC) is to limit the paracellular permeability by forming a selectively permeable barrier between the apical and basolateral compartment of the extracellular space. Impaired regulation of the TJC causes a variety of diseases, such as auto-immune diseases, cancer development, infections, allergies and asthma. The advantage of lanthanum as an opaque probe is its small ionic radius (0.11 nm), compared to alternative methods, such as radioactive isotope techniques using extracellular tracers and light microscopy techniques with larger polar molecules. This book presents a variety of biomedical applications of lanthanum.

Full Product Details

Author:   Harriet Nilsson ,  Anca Dragomir ,  Godfried M Roomans
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 23.00cm , Height: 0.50cm , Length: 15.50cm
Weight:   0.134kg
ISBN:  

9781617289064


ISBN 10:   161728906
Pages:   61
Publication Date:   08 March 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

Lanthanum as a tracer for the study of tight junctions; Structure & function of tight junctions; Methods to study the permeability of tight junctions in cell cultures; Lanthanum in the study of tight junctions in different tissues; Lanthanum as an inhibitor of ion channels; Uptake of lanthanum salts in the body; Lanthanum carbonate in the treatment of hyperphosphatemia in end stage renal disease; Index.

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