Overview

Despite the huge impact that biomaterials have had on patients' quality of life, improvements in device performance and the development of alternatives to augment available therapies are continuously being sought. This book explores the development and application of biomaterials over the past 25 years, examining the current clinical demand, the scientific rationale, and the technical challenges to be overcome. Furthermore, this book introduces the blood components involved in hemostasis and thrombosis, followed by the common biomaterials applied in blood-contacting devices. The complications induced by the interactions between blood and biomaterials is also briefly addressed, as well as the commonly used techniques for improving biomaterials' hemocompatibility. In addition, the authors give some valuable insight into calcium orthophosphate cements and concretes, as excellent biomaterials suitable for both dental and bone grafting application. Despite the growth of potential hydrogel based therapies, the route to market for new products is constrained by the need to develop an appropriate regulatory and metrological framework under which they will be assessed. This book outlines the role that metrology has to play in the regulation of emerging hydrogel-based therapies and detail possible strategies for assessing their safety and effectiveness. Other chapters examine the surface of CoCrMo alloy prior and after exposure into different solutions simulating oral conditions, recent research on delivery of gold nanoparticles inside the cells and their potential applications in nanomedicine, and the widely used biomedical applications for hydrogels.

Full Product Details

Author:   Henri Bourg ,  Amaury Lisle
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 26.00cm , Height: 3.60cm , Length: 18.00cm
Weight:   0.868kg
ISBN:  

9781608764761

ISBN 10:   1608764761
Pages:   497
Publication Date:   18 May 2010
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

Preface; Calcium Orthophosphate-Based Biocomposites & Hybrid Biomaterials; Calcium Orthophosphate Cements & Concretes; Hydrogels in Biology & Medicine; Biomaterials in Dentistry & Medicine; Biomaterials in blood-contacting devices: complications & solutions; Biocompatibility of Dental & Medical Materials; Enhanced Remineralisation of Subsurface Enamel Lesions with Functionalized a-TCP: Towards a Mechansim of Action; Translation of Emerging Hydrogel Therapies: The Role of Metrology; Metal Ion Release from the Base Co-Cr-Mo, Ni-Cr, & Noble Au-Pt Dental Alloy into the Buffered Solutions of Different Composition & pH Value; Co-Cr-Mo Alloy Surface Features & Composition Prior & After Mechanical Polishing & Corrosion in Fluids Simulating Oral Conditions; Intracellular Delivery of Gold Nanoparticles: Applications in Nanomedicine; A Commentary on Neural Tissue Engineering in the Central Nervous System -- Interfacing a Lesion; Index.

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