Overview
Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers. Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.
Full Product Details
Author: Dr Smita Pattanaik (Professor of Clinical Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India) ,
Dr Ashish Sharma (Professor and Head, Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research Chandigarh, India)
Publisher: Elsevier Science Publishing Co Inc
Imprint: Academic Press Inc
Weight: 0.450kg
ISBN: 9780128240694
ISBN 10: 0128240695
Pages: 356
Publication Date: 24 October 2025
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Author Information
Dr. Smita Pattanaik is a physician-scientist involved in teaching postgraduate students of clinical pharmacology and clinical patient care services, focusing on the delivery of precision medicine in clinics through therapeutic drug monitoring, pharmacogenomics, and model-informed precision dosing. Her research group, the Translational Pharmacology Laboratory, comprises clinicians, clinical scientists, and basic scientists. The goal is bedside-to-bench and bench-to-bedside translation involving immunosuppressant drugs (ISDs), the repositioning of drugs as anticancer agents, and collaborative clinical trials. Most of the current projects focus on organ transplantation, autoimmune diseases, and cancer. Ashish Sharma is a highly experienced transplant surgeon. He has more than 200 publications in national and international journals. He has been instrumental in starting academic training programs in kidney and pancreas transplant at PGIMER. Under his leadership, the department has been able to establish a pancreas transplant program, donation after cardiac death, along with a comprehensive surveillance and interventional vascular access program. He has been awarded by the Ministry of Health and the Indian Society of Organ Transplant for his exemplary services in transplant.
