Biologically Active Small Molecules: Modern Applications and Therapeutic Perspectives

Author:   Debarshi Kar Mahapatra ,  Sanjay Kumar Bharti
Publisher:   Apple Academic Press Inc.
ISBN:  

9781774910689


Pages:   368
Publication Date:   12 January 2023
Format:   Hardback
Availability:   In Print   Availability explained
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Biologically Active Small Molecules: Modern Applications and Therapeutic Perspectives


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Author:   Debarshi Kar Mahapatra ,  Sanjay Kumar Bharti
Publisher:   Apple Academic Press Inc.
Imprint:   Apple Academic Press Inc.
Weight:   0.775kg
ISBN:  

9781774910689


ISBN 10:   1774910683
Pages:   368
Publication Date:   12 January 2023
Audience:   Adult education ,  Further / Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

PART I: Small Molecules as Active Pharmacological Agents 1. Bedaquiline: The New Antituberculosis Drug on the Horizon 2. Plant-Derived Natural Products as Antiglycating Agents 3. Perspectives of Chalcone-Based Nf-Κβ Inhibitors as Anti-Inflammatory Agents 4. Coronaviruses: Molecular Modeling and Docking Studies of Potential Drug Candidates Showing Anti-Covid-19 Activity PART II: Pharmacotherapeutically Active Classes 5. Perspectives on Local Anesthetics in Medicine 6. Pharmacotherapeutic Perspectives on Adrenergic Agonists 7. Therapeutic Perspectives of Adrenergic Antagonists 8. Skeletal Muscle Relaxants: Concepts and Developments 9. Nonsteroidal Anti-Inflammatory Drugs: Concepts and Innovations PART III: Modern Approaches in Small Molecule Drug Discovery 10. Biological Databases: Tool for Low Molecular Weight Ligand Discovery Process 11. High-Throughput Screening Technique: Role in the Drug Discovery of Low Molecular Weight Ligands 12. Homology Modeling: Applications in the Low Molecular Weight Ligand Designing PART IV: Biopharmaceutics Approaches for Low Molecular Weight Ligands 13. Drug Metabolism: Detoxification and Xenobiotic Biotransformation 14. Drug Interactions: Highlights of Adverse Effects of Low Molecular Weight Ligands PART V: Evaluation Methods for Small Molecules 15. Low Molecular Weight Antioxidant Agents and Model for Their Evaluation

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Author Information

Debarshi Kar Mahapatra, PhD, is currently an assistant professor in the Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India. He taught medicinal chemistry and computational chemistry at both undergraduate (UG) and postgraduate (PG) levels and has mentored a number of students in various research projects. His area of interest includes computer-assisted rational designing, synthesis of low molecular weight ligands against druggable targets, development of drug delivery systems, and optimization of unconventional formulations. He has published several research papers, review articles, imperative case-studies in various reputed international journals and has presented his original contributions at several international platforms, for which he received several awards by a number of scientific and professional bodies. He has been recognized as Top 2% International Scientists in the S7 List published by Stanford University in the year 2020 with sub-field ranking of 1407. He has contributed several edited books, syllabus-based textbooks, lab manuals, book chapters, magazine articles, and guidebooks on pharmaceutical chemistry, natural products, pharmacology, and pharmaceutics. Presently, he is serving as an approved reviewer and an editorial board member for several journals of international repute. He is an active member of a number of professional and international scientific societies such as ISCA, ISID, ISEI, IPS, APTI, HSGPP, ISPOR, IPS, ISAS, SPER, IPES, etc. He is serving the positions of Chief Advisor and Chief Executive Manager for Indian Pharma Educational Society (IPES), India. In addition to it, he is presently serving as Vice President for Expert Pharmacy Association (EPA), India. Sanjay Kumar Bharti, PhD, is an assistant professor at the Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India. He has working experience in several organizations, such as Win-Medicare Pvt. Ltd, Meerut, India (as a chemist) and the National Institute of Pharmaceutical Education and Research (NIPER), Hajipur (as a lecturer). He has published several research papers, one book, several book chapters, and several review articles in various reputed journals. His research interest includes synthesis of Schiff’s base, heterocyclic compounds, and metallopharmaceuticals for therapeutics. He is an active member of various scientific and pharmaceutical organizations, including the Indian Pharmaceutical Association, Indian Pharmacy Graduates’ Association, Indian Science Congress Association, among others.

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