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Author:   Richard S. Larson ,  Tudor I. Oprea
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   3rd ed. 2019
Volume:   1939
Weight:   0.858kg
ISBN:  

9781493990887

ISBN 10:   1493990888
Pages:   324
Publication Date:   09 March 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface... Table of Contents... Contributing Authors... Part I Translational Bioinformatics in Drug Discovery 1. Miniaturized Checkerboard Assays to Measure Antibiotic Interactions Melike Cokol-Cakmak and Murat Cokol 2. High-Throughput Screening for Drug Combinations Paul Shinn, Lu Chen, Marc Ferrer, Zina Itkin, Carleen Klumpp-Thomas, Crystal McKnight, Sam Michael, Tim Mierzwa, Craig Thomas, Kelli Wilson, Rajarshi Guha 3. Post-Processing of Large Bioactivity Data Jason Bret Harris 4. How to Develop a Drug Target Ontology: KNowledge Acquisition and Representation Methodology (KNARM) Hande Kucuk-McGinty, Ubbo Visser, and Stephan Schurer S. Part II Informatics in Drug Discovery 5. A Guide to Dictionary-Based Text Mining Helen V. Cook and Lars Juhl Jensen 6. Leveraging Big Data to Transform Drug Discovery Benjamin S. Glicksberg, Li Li, Rong Chen, Joel T. Dudley, and Bin Chen 7. How to Prepare a Compound Collection Prior to Virtual Screening Cristian G. Bologa, Oleg Ursu, and Tudor I. Oprea 8. Building a Quantitative Structure-Property Relationship (QSPR) Model Robert D. Clark and Pankaj R. Daga 9. Isomeric and Conformational Analysis of Small Drug and Drug-Like Molecules by Ion Mobility Mass Spectrometry (IM-MS) Shawn T. Phillips, James N. Dodds, Jody C. May, and John A. McLean Part III Clinical Research Informatics in Drug Discovery 10. A Computational Platform and Guide for Acceleration of Novel Medicines and Personalized Medicine Ioannis N. Melas, Theodore Sakellaropoulos, Junguk Hur, Dimitris Messinis, Ellen Y. Guo, Leonidas G. Alexopoulos, Jane P.F. Bai 11. Omics Data Integration and Analysis for Systems Pharmacology Hansaim Lim and Lei Xie 12. Bioinformatics Based Tools and Software in Clinical Research: A New Emerging Area Parveen Bansal, Malika Arora, Vikas Gupta, and Mukesh Maithani 13. Text Mining for Drug Discovery Si Zheng, Shazia Dharssi, Meng Wu, Jiao Li, Zhiyong Lu Part IV Clinical Informatics in Drug Discovery 14. Big Data Cohort Extraction for Personalized Statin Treatment and Machine Learning Terrence J. Adam and Chih-Lin Chi 15. Drug Signature Detection Based on L1000 Genomic and Proteomic Big Data Wei Chen and Xiaobo Zhou 16. Drug Effect Prediction by Integrating L1000 Genomic and Proteomic Big Data Wei Chen and Xiaobo Zhou 17. A Bayesian Network Approach to Disease Subtype Discovery Mei-Sing Ong

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