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Author:   Richard S. Larson
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 2nd ed. 2012
Volume:   910
Weight:   0.998kg
ISBN:  

9781493959297

ISBN 10:   1493959298
Pages:   374
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Cell Perturbation Screens for Target Identification by RNAi.-Using Functional Genomics to Identify Drug Targets: a Dupuytren’s Disease Example.-Functional Characterization of Human Genes from Exon Expression and RNA Interference Results.-Barcode Sequencing for Understanding Drug-gene Interactions.-High-Throughput Sequencing of the Methylome Using Two-Base Encoding.-Applications and Limitations of In Silico Models In Drug Discovery.-Compound Collection Preparation for Virtual Screening.-Mapping Between Databases of Compounds and Protein Targest.-Predictive Cheminformatics in Drug Discovery: Statistical Modeling for Analysis of Micro-Array and Gene Expression Data.-Advances in Nuclear Magnetic Resonance for Drug Discovery.-Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance.-Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection.-Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis.-Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes.-Integration of Multiple Ubiquitin Signals in Proteasome Regulation.  

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