Overview

In the present book, after briefly summarising recent literature concerning modification and applications of these materials, several recent developments of bio-composites containing silica nanoparticles or calcium sulphate intended for bone regeneration are reported. The composites are characterised with respect to their chemical-physical and mechanical properties. Their bio-compatibility and capacity to induce the osteoblastic phenotype in human bone marrow mesenchymal stem cells have been assessed. The authors focus on two particular systems based on either natural or synthetic bio-polymers with different biofillers: alginate/chitosan blends with calcium sulphate and poly(-caprolactone) with silica nanoparticles.

Full Product Details

Author:   Luigi Calandrelli ,  Paola Laurienzo ,  Mario Malinconico
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 23.00cm , Height: 0.80cm , Length: 15.50cm
Weight:   0.144kg
ISBN:  

9781608769575

ISBN 10:   1608769577
Pages:   72
Publication Date:   01 July 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

Introduction; Principles of Tissue Engineering; Biocompatibility Testing of Medical Devices: ""Tests for In-Vitro Cytotoxicity (EN ISO 10993-5)""; Principles of Synthetic Bone Substitutes; Polymers for Bone Tissue Engineering; Silica-Based Materials & Nanoparticles for Bone Regeneration; The Use of Calcium Sulphate in Bone Regeneration; Realization & Performance Analysis of PCL/ Silica Nanocomposites for Bone Regeneration; Mechanical Alloys (Chemical Physical & Mechanical Properties); Chemical Modification & Characterization of Nanocomposites; Morphologic Analysis (SEM); Biological Evaluation; Experimental; Materials; Preparation of Silica Nanoparticles; Preparation of Nanocomposites; Differential Thermal Analysis (DSC); Preparation & Characterization of Bone Marrow MSCs; Novel Injectable Alginate/N-Succinylchitosan/ Calcium Sulphate Composites as Bone-Defects; Biological Evaluation; Index.

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