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OverviewFull Product DetailsAuthor: Bernard Testa (University Hospital Centre, Lausanne, Switzerland) , John CaldwellPublisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Dimensions: Width: 17.80cm , Height: 2.50cm , Length: 25.40cm Weight: 0.890kg ISBN: 9780126853919ISBN 10: 0126853916 Pages: 471 Publication Date: 25 October 1994 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Out of Print Availability: In Print ![]() Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of ContentsXenobiotic Metabolism: The Global View. Xenobiotic Metabolism: The Biochemical View. Dehydrogenation of Alcohols and Aldehydes, Carbonyl Reduction. The Nature and Functioning of Cytochromes P450 and Flavin-Containing-Monooxygenases. Carbon Oxidations Catalyzed by Cytochromes P450. Monooxygenase-Catalyzed N-C Cleavage. Monooxygenase-Catalyzed Oxidation of Oxygen- and Sulfur-Containing Compounds. Oxidative Dehalogenation and Dealkylation of Organometallics. Oxidations Catalyzed by Various Oxidases and Monooxygenases. Reactions Catalyzed by Peroxidases. Oxidation of Mercury, Silicon, Phosphorus, Arsenic, Selenium, and Halogens. Reductions Catalyzed by Cytochrome P450 and Other Oxidoreductases. Various Enzymatic and Nonenzymatic Reactions. Conclusion and Outlook.ReviewsWhat I really like and what I would like to emphasize is the fact that this book is not only a comprehensive collection of biochemical data on redox mechanisms, but is legible as well. The personal style and the commitment of the author that can be felt between the lines contributes to my unreserved recommendation to have this book on the shelf of everyone who is busy in the field of making compounds that interact with living systems. --Pharmaceutica Acta Helvetiae Testa's deep comprehension of his subject and his scholarly commitment make sure that this volume is not only comprehensive but eminently readable. --SIR JAMES BLACK, Nobel Laureate ...several books have appeared on the metabolism of xenobiotic compounds, but this new text, by one of the most respected researchers in the field, has set the benchmark for all that follow... indispensible to all serious students of drug metabolims, and a collection to treasure. --Laurence J. Kim, University of Surrey, in ISSX NEWSLETTER The overall impression is one of a book that is extensively and well researched with the facts clearly laid out in a very readable style. --David Needham in BRITISH TOXICOLOGY SOCIETY NEWSLETTER The book would be very applicable as a text or reference for graduate and advanced undergraduate courses in toxicology, drug metabolism, medicinal chemistry and pharmacy. Professor Testa has done a very admirable job of compiling and presenting material of the subject. The book is strongly recommended as a course text and general reference, and I look forward to seeing the remaining three volumes in the series. --F. Peter Guengerich in PHARMACEUTICAL NEWS What I really like and what I would like to emphasize is the fact that this book is not only a comprehensive collection of biochemical data on redox mechanisms, but is legible as well. The personal style and the commitment of the author that can be felt between the lines contributes to my unreserved recommendation to have this book on the shelf of everyone who is busy in the field of making compounds that interact with living systems. --Pharmaceutica Acta Helvetiae Testa's deep comprehension of his subject and his scholarly commitment make sure that this volume is not only comprehensive but eminently readable. --SIR JAMES BLACK, Nobel Laureate ...several books have appeared on the metabolism of xenobiotic compounds, but this new text, by one of the most respected researchers in the field, has set the benchmark for all that follow... indispensible to all serious students of drug metabolims, and a collection to treasure. --Laurence J. Kim, University of Surrey, in ISSX NEWSLETTER The overall impression is one of a book that is extensively and well researched with the facts clearly laid out in a very readable style. --David Needham in BRITISH TOXICOLOGY SOCIETY NEWSLETTER The book would be very applicable as a text or reference for graduate and advanced undergraduate courses in toxicology, drug metabolism, medicinal chemistry and pharmacy. Professor Testa has done a very admirable job of compiling and presenting material of the subject. The book is strongly recommended as a course text and general reference, and I look forward to seeing the remaining three volumes in the series. --F. Peter Guengerich in PHARMACEUTICAL NEWS Author InformationTab Content 6Author Website:Countries AvailableAll regions |