Overview

Our understanding of inflammation has increased rapidly in recent years, due in large part to the impact of molecular biology and gene identification and cloning. This book brings together ideas from a number of different biochemical disciplines which are frequently not integrated. The first chapter gives a visual overview of the subject; the remaining chapters are organized into three themes: the affector molecules, the regulatory components and the processes of inflammation itself. This book is essential reading for the busy physician or pathologist who wants to be up-to-date with the latest developments in immunology as they affect the diagnosis and treatment of many conditions.

Full Product Details

Author:   J. Whicher ,  S.W. Evans
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 1992
Volume:   18
Dimensions:   Width: 15.50cm , Height: 1.70cm , Length: 23.50cm
Weight:   0.504kg
ISBN:  

9789401053327

ISBN 10:   9401053324
Pages:   313
Publication Date:   12 October 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1 An overview of the inf lammatory response.- 2 The complement system and inflammation.- 3 The kinin system: current concepts and perspectives.- 4 Role of cellular proteinases and their protein inhibitors in inflammation.- 5 Eicosanoids (prostaglandins and leukotrienes).- 6 The role of toxic oxygen species in inflammation with special reference to DNA damage.- 7 Glucocorticoids and lipocortin.- 8 Platelet activating factor and cytokine feedback regulation ofendothelial integrity: implications for the treatment of inflammatory disease.- 9 A role for neuropeptides in inflammation.- 10 Interleukin 1 as an inflammatory mediator.- 11 Tumour necrosis factor (TNF) and inflammation.- 12 Interleukin 6: a consequence of inflammation.- 13 The acute phase response.- 14 The role of leukocyte chemotaxis in inflammation.

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