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Author:   Takehiko Yokomizo ,  Makoto Murakami
Publisher:   Springer Verlag, Japan
Imprint:   Springer Verlag, Japan
Edition:   1st ed. 2015
Dimensions:   Width: 15.50cm , Height: 2.80cm , Length: 23.50cm
Weight:   8.535kg
ISBN:  

9784431556688

ISBN 10:   4431556680
Pages:   426
Publication Date:   05 November 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

PART I ENZYMES AND RECEPTORS FOR LIPID MEDIATORS.- 1 Lysophospholipid Acyltransferases.- 2 Phospholipase A2.- 3 Prostaglandin Terminal Synthases as Novel Drug Targets.- 4 Pathophysiological Roles of Prostanoid Receptors in the Central Nervous System.- 5 Lipoxygenases: A Chronological Perspective on the Synthesis of S and R Fatty Acid Hydroperoxides.- 6 Leukotriene B4 Receptors.- 7 Platelet-Activating Factor (PAF) in Infectious Diseases.- 8 Lysophospholipid Mediators: Their Receptorsand Synthetic Pathways.- 9 Sphingolipid Metabolism via Sphingosine 1-Phosphate and Its Role in Physiology, Pathology, and Nutrition.- 10 Fatty Acids Receptors.- 11 Omega-3 Fatty Acid Metabolism and Regulation of Inflammation.- PART II LIPID MEDIATORS IN DROSOPHILA AND ZEBRAFISH.- 12 Membrane Lipid Transporters in Drosophila melanogaster.- 13 Drosophila: A Model for Studying Prostaglandin Signaling.- 14 Zebrafish as a Model Animal for Studying Lysophosphatidic Acid Signaling.- 15 Sphingosine 1-Phosphate Signaling via Transporters in Zebrafish and Mice.- PART III LIPID MEDIATORS AND DISEASES.- 16 Lipid Mediator LPA-Induced Demyelination and Self-Amplification of LPA Biosynthesis in Chronic Pain Memory Mechanisms.- 17 Vascular Endothelial S1P2 Receptor Limits Tumor Angiogenesis and Hyperpermeability.- 18 Roles of Prostaglandins in Regulation of Pathological Angiogenesis and Lymphangiogenesis.- 19 Eicosanoids and Aortic Aneurysm.- 20 Cysteinyl Leukotrienes and Disease.- 21 Lipid Mediators and Skin Diseases.- 22 Roles and Actions of Arachidonic Acid-Derived Bioactive Lipids in Stress-Related Behaviors.- PART IV PROTOCOLS FOR ANALYZING LIPID MEDIATORS.- 23 Basic Techniques for Lipid Extraction from Tissues and Cells.- 24 Comprehensive Analysis of Eicosanoids.- 25 Mass Spectrometric Analysis of Phospholipids by Target Discovery Approach.- 26 Determination of Sphingolipids by LC-MS/MS.- 27 Lipid Machinery Investigation Using MALDI Imaging Mass Spectrometry. 28 Measuring Activationof Lipid G Protein-Coupled Receptors Using the TGF-α Shedding Assay.- 29 A Novel Anti-FLAG Monoclonal Antibody is Useful to Study GPCRs.- Index.

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