Bioactive Heterocycles V

Author:   Mahmud Tareq Hassan Khan
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of hardcover 1st ed. 2007
Volume:   11
ISBN:  

9783642092466


Pages:   335
Publication Date:   19 November 2010
Format:   Paperback
Availability:   Out of print, replaced by POD   Availability explained
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Bioactive Heterocycles V


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Overview

This volume contains 10 chapters. The contributions are from researchers - mousintheirrespective?eldsandthechapterscontainhighqualityreviewson topics related to the chemo-biologicalstudies of several different heterocyclic groups. The ?rst chapter from Saracoglu reviews the functionalization of indoles andthepyrrolesviaMichaeladditions,asthesecompoundshavepotential for their biologicalactivities. InsecondchapterMen' endezreviewsthechemistryofthewelwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis andrecent strategiesforthesynthesisoflignans.Lignansareaveryimportant classofmolecules,astheyhaveaverydiversespectrumofbiologicalactivities, such as antitumour, antiviral, hepatoprotective, antioxidant, antiulcer, an- allergen, anti-platelet, and anti-osteoporoticactivities. InnextchapterSuzen .. describestheantioxidantactivitiesofsyntheticindole derivatives and their possible mechanisms of action. Inchapter?veGonz' alezetal.presentsacomprehensivereviewonthech- istry and biology of the quinoxaline 1,4-dioxide and phenazine 5,10-dioxide typemolecules.Theyalsodiscussthemodeofaction,structure-activitystudies andother relevant chemical andbiologicalproperties forsuch molecules. Inthechaptersix,Khanbrie?ydiscussestheanti-angiogenicandtelomerase inhibitory activities of quinoline and its analogues. Liuet al.,inchapterseven, brie?y reviewssomeaspects ofstudies ofbio- tive marine sponge furanosesterterpenoids from the last 10 years, including their totalsyntheses. Pujol et al. in chapter eight, reviews the chemistry, origin and antiviral activities of naturally occurring sulfated polysaccharides for the prevention and controlof viral infections such as HIV-1 and -2, human cytomegalovirus (HCMV), dengue virus (DENV), respiratory syncytial virus (RSV), and - ?uenza Avirus. InchapternineHamdietal.describesthesynthesisandbiologicalactivities of the heterocyclicand vanillin ether coumarins. In the last chapter, Orhan et al. reviews their recent ?ndings on antiviral and antimicrobial heterocyclic compounds fromTurkish plants. Tromso,Norway 2007 Mahmud Tareq Hassan Khan Contents FunctionalizationofIndoleandPyrroleCores viaMichael-TypeAdditions N.Saracoglu ...1 ChemistryoftheWelwitindolinones J.C.Menendez ...63 LignansFrom TaxusSpecies G.Topcu*O.Demirkiran...103 AntioxidantActivities ofSyntheticIndoleDerivatives andPossibleActivity Mechanisms S.Suzen...1 45 Quinoxaline 1,4-DioxideandPhenazine5,10-Dioxide.

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Author:   Mahmud Tareq Hassan Khan
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of hardcover 1st ed. 2007
Volume:   11
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.539kg
ISBN:  

9783642092466


ISBN 10:   3642092462
Pages:   335
Publication Date:   19 November 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of print, replaced by POD   Availability explained
We will order this item for you from a manufatured on demand supplier.

Table of Contents

Functionalization of Indole and Pyrrole Cores via Michael-Type Additions.- Chemistry of the Welwitindolinones.- Lignans From Taxus Species.- Antioxidant Activities of Synthetic Indole Derivatives and Possible Activity Mechanisms.- Quinoxaline 1,4-Dioxide and Phenazine 5,10-Dioxide. Chemistry and Biology.- Quinoline Analogs as Antiangiogenic Agents and Telomerase Inhibitors.- Bioactive Furanosesterterpenoids from Marine Sponges.- Natural Sulfated Polysaccharides for the Prevention and Control of Viral Infections.- 4-Hydroxy Coumarine: a Versatile Reagent for the Synthesis of Heterocyclic and Vanillin Ether Coumarins with Biological Activities.- Antiviral and Antimicrobial Evaluation of Some Heterocyclic Compounds from Turkish Plants.

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