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OverviewThis volume contains 10 chapters. The contributions are from researchers - mousintheirrespective?eldsandthechapterscontainhighqualityreviewson topics related to the chemo-biologicalstudies of several different heterocyclic groups. The ?rst chapter from Saracoglu reviews the functionalization of indoles andthepyrrolesviaMichaeladditions,asthesecompoundshavepotential for their biologicalactivities. InsecondchapterMen' endezreviewsthechemistryofthewelwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis andrecent strategiesforthesynthesisoflignans.Lignansareaveryimportant classofmolecules,astheyhaveaverydiversespectrumofbiologicalactivities, such as antitumour, antiviral, hepatoprotective, antioxidant, antiulcer, an- allergen, anti-platelet, and anti-osteoporoticactivities. InnextchapterSuzen .. describestheantioxidantactivitiesofsyntheticindole derivatives and their possible mechanisms of action. Inchapter?veGonz' alezetal.presentsacomprehensivereviewonthech- istry and biology of the quinoxaline 1,4-dioxide and phenazine 5,10-dioxide typemolecules.Theyalsodiscussthemodeofaction,structure-activitystudies andother relevant chemical andbiologicalproperties forsuch molecules. Inthechaptersix,Khanbrie?ydiscussestheanti-angiogenicandtelomerase inhibitory activities of quinoline and its analogues. Liuet al.,inchapterseven, brie?y reviewssomeaspects ofstudies ofbio- tive marine sponge furanosesterterpenoids from the last 10 years, including their totalsyntheses. Pujol et al. in chapter eight, reviews the chemistry, origin and antiviral activities of naturally occurring sulfated polysaccharides for the prevention and controlof viral infections such as HIV-1 and -2, human cytomegalovirus (HCMV), dengue virus (DENV), respiratory syncytial virus (RSV), and - ?uenza Avirus. InchapternineHamdietal.describesthesynthesisandbiologicalactivities of the heterocyclicand vanillin ether coumarins. In the last chapter, Orhan et al. reviews their recent ?ndings on antiviral and antimicrobial heterocyclic compounds fromTurkish plants. Tromso,Norway 2007 Mahmud Tareq Hassan Khan Contents FunctionalizationofIndoleandPyrroleCores viaMichael-TypeAdditions N.Saracoglu ...1 ChemistryoftheWelwitindolinones J.C.Menendez ...63 LignansFrom TaxusSpecies G.Topcu*O.Demirkiran...103 AntioxidantActivities ofSyntheticIndoleDerivatives andPossibleActivity Mechanisms S.Suzen...1 45 Quinoxaline 1,4-DioxideandPhenazine5,10-Dioxide. Full Product DetailsAuthor: Mahmud Tareq Hassan KhanPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of hardcover 1st ed. 2007 Volume: 11 Dimensions: Width: 15.50cm , Height: 1.80cm , Length: 23.50cm Weight: 0.539kg ISBN: 9783642092466ISBN 10: 3642092462 Pages: 335 Publication Date: 19 November 2010 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Out of print, replaced by POD ![]() We will order this item for you from a manufatured on demand supplier. Table of ContentsFunctionalization of Indole and Pyrrole Cores via Michael-Type Additions.- Chemistry of the Welwitindolinones.- Lignans From Taxus Species.- Antioxidant Activities of Synthetic Indole Derivatives and Possible Activity Mechanisms.- Quinoxaline 1,4-Dioxide and Phenazine 5,10-Dioxide. Chemistry and Biology.- Quinoline Analogs as Antiangiogenic Agents and Telomerase Inhibitors.- Bioactive Furanosesterterpenoids from Marine Sponges.- Natural Sulfated Polysaccharides for the Prevention and Control of Viral Infections.- 4-Hydroxy Coumarine: a Versatile Reagent for the Synthesis of Heterocyclic and Vanillin Ether Coumarins with Biological Activities.- Antiviral and Antimicrobial Evaluation of Some Heterocyclic Compounds from Turkish Plants.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |