Beta-Catenin: Structure, Function & Clinical Significance
Author:   Abel Braunfeld ,  Gabriel R Mirsky
Publisher:   Nova Science Publishers Inc
ISBN:  

9781628088014


Pages:   178
Publication Date:   01 December 2013
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Beta-Catenin: Structure, Function & Clinical Significance


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Overview

ss-catenin is a multifunctional protein required in both cell-cell adherens junctions and canonical Wnt signalling. It is involved in a variety of developmental processes and is critical in heart development, one of the first functional organs to develop during vertebrate embryogenesis. In this book, the authors discuss the structure, function and clinical significance of ss-catenin. Topics include the role of ss-Catenin in the context of oral squamous cell carcinoma and its clinical implications; how ss-Catenin/TCF4/Survivin signalling determines the properties and fate of human corneal epithelial stem cells; ss-Catenin in kidney fibrosis and cardiovascular development; the role of ss-Catenin in eye development, infection and inflammation; targeting the canonical Wnt/Beta-Catenin signalling pathway in hematological malignancies; and the clinical significance of Beta-Catenin in immunological disease and dysfunction.

Full Product Details

Author:   Abel Braunfeld ,  Gabriel R Mirsky
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Weight:   0.422kg
ISBN:  

9781628088014


ISBN 10:   162808801
Pages:   178
Publication Date:   01 December 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Preface; The Role of ss-Catenin in the Context of Oral Squamous Cell Carcinoma & its Clinical Implications; ss-Catenin/TCF4/Survivin Signaling Determine the Properties & Fate of Human Corneal Epithelial Stem Cells; ss-Catenin & Kidney Fibrosis; Beta-Catenin & Cardiovascular Development; The Role of ss-Catenin in Eye Development; The Novel Roles of ss-Catenin in Infection & Inflammation; Targeting the Canonical Wnt/Beta-Catenin Signaling Pathway in Hematological Malignancies; Clinical Significance of Beta-Catenin in Immunological Disease & Dysfunction: Signaling & Therapy; Index.

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