Overview

This book is an ideal text on PET imaging technology that focuses on the basics, such as physics, instrumentation, production of PET radionuclides and radiopharmaceuticals, and regulations affecting PET. The chapters are concise but comprehensive, making the topic easily understandable, and they are complete with reviews of pertinent basic science and lists of suggested reading. Practical tables and appendixes contain a wealth of valuable data, reflecting the book's usefulness as a reference for nuclear medicine professionals, including physicians, residents, and technologists. The book also benefits technologists and residents preparing for board examinations because of its brevity and clarity of content.

Full Product Details

Author:   Gopal B. Saha
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2005 ed.
Weight:   0.346kg
ISBN:  

9781441919441

ISBN 10:   1441919449
Pages:   224
Publication Date:   15 October 2010
Audience:   General/trade ,  Professional and scholarly ,  General ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Preface Chapter 1Radioactive Decay and Interaction of Radiation with Matter Atomic StructureRadioactive DecayGeneral Radioactive Decay EquationsSuccessive Decay EquationsUnits of RadioactivityUnits of Radioactivity in System InternationaleCalculationInteraction of Radiation with Matter Interaction of Charged Particles with Matter Interaction of ( Radiation with Matter Attenuation of ( RadiationsQuestionsReferences and Suggested Reading Chapter 2PET Scanning Systems Background Solid Detectors in PET Photomultiplier Tube Pulse Height Analyzer Arrangement of Detectors PET Scanners Hybrid Scintillation Cameras PET/CT Scanners Small Animal PET Scanner Mobile PETQuestionsReferences and Suggested Reading Chapter 3Data Acquisition and Corrections Data Acquisition Two-dimensional versus three-dimensional PET/CT data acquisitionFactors Affecting Acquired Data Normalization Photon Attenuation Random Coincidences Scatter Coincidences Dead Time Radial ElongationQuestionsSuggested Reading Chapter 4Image Reconstruction, Storage and Display Simple BackprojectionFiltered Backprojection The Convolution Method The Fourier Method Types of FiltersIterative Reconstruction3-D ReconstructionPartial Volume EffectStorageDisplaySoftware and DICOMPACSTeleradiologyQuestionsReferences and Suggested Reading Chapter 5Performance Characteristics of PET Scanners Spatial ResolutionSensitivityNoiseScatter FractionContrastQuality Control of PET Scanners Daily Quality Control Tests Weekly Quality Control TestsAcceptance Tests Spatial Resolution Sensitivity Scatter Fraction Count Rate Losses and Random CoincidencesQuestionsReferences and Suggested Reading Chapter 6Cyclotron and Production of PET Radionuclides Cyclotron OperationTarget and its ProcessingEquation for Production of RadionuclidesSpecific ActivityProduction of Short-lived Positron-emitters Fluorine-18 Carbon-11 Nitrogen-13 Oxygen-15 Iodine-124 Strontium-82 Technetium-94mQuestionsSuggested Reading Chapter 7Synthesis of PET Radiopharmaceuticals PET Radiopharmaceuticals 18F-Sodium Fluoride 18F-Fluorodeoxyglucose (FDG) 6-18F-L-Fluorodopa 18F-Fluorothymidine (FLT) 15O-Water n-15O-Butanol 13N-Ammonia 11C-Sodium Acetate 11C-Flumazenil 11C-Methylspiperone (MSP) 11C-L-Methonine 11C-Raclopride 82Rb-Rubidium ChlorideAutomated Synthesis DevicesQuality Control of PET RadiopharmaceuticalsSpecifications for Routine PET Radiopharmaceuticals 18F-FDG 6-18F-L-Fluorodopa 13N-AmmoniaQuestionsReferences and Suggested Reading Chapter 8Regulations Governing PET Radiopharmaceuticals Food and Drug Administration Radioactive Drug Research CommitteeRadiation Regulations for PET Radiopharmaceuticals License or Registration Regulations for Radiation ProtectionPrinciples of Radiation Protection Time Distance Shielding Activity Do's and Don'ts in Radiation Protection PracticeDepartment of TransportationDistribution of 18F-FDGQuestionsReferences and Suggested Reading Chapter 9Reimbursement for PET Procedures BackgroundCoverageCoding CPT, HCPCS and APC Codes ICD-9-CM CodesPayment Hospital Inpatient Services -- Medicare Hospital Outpatient Services -- Medicare Freestanding Imaging Center -- Medicare Non-Medicare Payers -- all settingsBilling Billing ProcessChronology of PET ReimbursementQuestionsReferences and Suggested Reading Chapter 10Design and Cost of PET Center Site PlanningPassagePET Center PET Scanner Section Cyclotron Section Office AreaCaveatShielding Case StudyCost of PET OperationQuestionsReferences and Suggest Reading Chapter 11Procedures for PET Studies Whole Body PET Imaging with 18F-FDGWhole Body PET/CT imaging with 18F-FDGMyocardial Perfusion Imaging with 82RbMyocardial Metabolic Imaging with 18F-FDGAddendum 82Rb Infusion Pump Appendix A.Abbreviations Used in the TextAppendix B.Terms Used in the TextAppendix C.Units and ConstantsAppendix D.Estimated Absorbed Doses From Intravenous Administration of 18F-FDG and 82Rb-RbClAppendix E.Evaluation of Tumor Uptake of 18F-FDG by PETAppendix F.Answers to Questions Index

Reviews

From the reviews: Gives a clear and concise overview of basic physics and PET instrumentation, the theory of image processing and attenuation correction, scanner performance and testing, cyclotron production and synthesis of PET radiopharmaceuticals ! . These subjects are not often covered in a single volume and make the book useful ! . up to date as possible in a rapidly evolving field ! . The question and answer sections at the end of each chapter would be an aid in self-learning. (M J Myers, RAD Magazine, July, 2005) This book presents the fundamentals of PET imaging in a very practical and concise, but also exhaustive way. ! The book is very informative and represents a helpful reference text for nuclear medicine technologists, nuclear medicine residents and nuclear medicine physicians, and, given its clarity and simplicity, for all those willing to familiarize themselves with the fundamentals of PET imaging. (M. C. Gilardi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 33 (1), 2006) This is an up-to-date short manual that reviews the fundamentals of PET imaging. The chapters are sufficiently comprehensive to make the topic easily understandable ! . The text is concise and accompanied by tables, appendixes ! making the book a valuable reference ! . a self-evaluation section is available with a set of short questions that helps the reader to assess the sufficiency of knowledge gained. Residents taking board examinations would particularly benefit ! . Overall, this is an excellent short manual ! . (A. Manrique, Surgical and Radiologic Anatomy, Vol. 27 (4), 2005) Dr. Gopal B. Saha has written a clear and concise primer on PET. This text would be excellent for technologists, residents, or physicians who want to become familiar with the basics of PET and would also be an ideal reference for anyone preparing for accreditation examinations. ! Several photographs, diagrams, and tables further each discussion. ! I found this book to be of great value both in content and in price. (Colleen M. Nall, Journal of Nuclear Medicine Technology, Vol. 34 (1), 2006)

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