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OverviewBacterial pili play important roles as environmental sensors, in host colonization and in biofilm formation, enabling bacteria to interact with the environment, with surfaces and with other bacteria and host cells. Most bacteria, both Gram positive and Gram negative, and almost all bacterial pathogens, are piliated. This book discusses the synthesis, structure, evolution, function and role in pathogenesis of these complex structures, and their basis for vaccine development and therapeutics for Streptococcus pathogens. It is an invaluable resource for researchers and students of medical microbiology. Full Product DetailsAuthor: Michele A Barocchi (Novartis Vaccines & Diagnostics Srl) , John Telford (formerly Novartis Vaccines & Diagnostics Srl, Italy)Publisher: CABI Publishing Imprint: CABI Publishing Edition: 1 Dimensions: Width: 17.20cm , Height: 1.70cm , Length: 24.40cm Weight: 0.641kg ISBN: 9781780642550ISBN 10: 1780642555 Pages: 224 Publication Date: 07 April 2014 Audience: College/higher education , Professional and scholarly , Tertiary & Higher Education , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsA: Table of Contents B: Foreword Sixty Years of Pilus research 1: The Vibrio cholerae toxin coregulated pilus: structure, assembly and function with implications for vaccine design 2: Conjugative pili 3: Pilus biogenesis by the chaperone-usher pathway 4: Type 1 and P Pili of Uropathogenic Escherichia coli 5: Type IV pili: functions and biogenesis 6: The Pseudomonas aeruginosa type IV pilus assembly system in three dimensions 7: Corynebacterium diphtheriae pili: Assembly, Structure, and Function 8: Three-dimensional structures of pilin subunits and their role in Gram-positive pilus assembly and stability 9: Sortase structure and specificity in Streptococci 10: Pili of Streptococcus pyogenes 11: The role of pili in the formation of biofilm and bacterial communities 12: Fimbrae/Pili from oral bacteria 13: Pilus based vaccine development in Streptococci: Variability, Diversity & Immunological responsesReviewsAuthor InformationMichele A. Barocchi: Head, Molecular Epidemiology Unit, Novartis Vaccines & Diagnostics srl John L. Telford: Head, Microbial Molecular Biology, Novartis Vaccines & Diagnostics srl Tab Content 6Author Website:Countries AvailableAll regions |