Overview
Automation is the major future trend for many areas in microbiology, molecular biology, and biochemistry, among other disciplines. It is an enormously exciting area, where techniques and assays that were once repetitive, tedious, and time consuming can be performed robotically, liberating the time of researchers and hospital laboratory workers for more interesting work. Many techniques have now been automated and often miniaturized, including PCR analysis, DNA/RNA preparation, diagnostic test (e.g., Pap tests), compound screening, and of course, sequencing. Some major advances, notably in Professor Leroy Hood's group, have resulted in the ability to perform thousands of assays simultaneously on a normal microscope slide. Automation, edited by two of the leading experts in the field, presents the very latest experimental techniques explained in detail. This book has succeeded in bringing together researchers at the forefront of clone library construction, genome analysis, sequencing, computational data evaluation and functional analysis, to provide insight into this new age of research based on genomic and chemical screening.
Full Product Details
Author: Alister G. Craig (Liverpool School of Tropical Medicine, Liverpool, U.K.) , Jörg D. Hoheisel (Functional Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany)
Publisher: Elsevier Science Publishing Co Inc
Imprint: Academic Press Inc
Volume: 28
Dimensions:
Width: 16.50cm
, Height: 1.80cm
, Length: 24.10cm
Weight: 0.590kg
ISBN: 9780125215275
ISBN 10: 0125215274
Pages: 270
Publication Date: 08 December 1998
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Out of Print
Availability: In Print 
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.
Table of Contents
L. Hood, Foreword. U. Pettersson, Introduction. A. Fife and D.W.M. Crook, Automation in Clinical Microbiology. A.J.McCollum, Vision Systems for Automated Colony and Plaque Picking. D.R. Bancroft, E. Maier and H. Lehrach, Library Picking, Presentation and Analysis. G. Kauer and H. Blöcker, The PREPSEQ Robot: An Integrated Environment for Fully Automated and Unattended Plasmid Preparations and Sequencing Reactions. A.N. Hale, Building Realistic Automated Production Lines for Genetic Analysis. A.N. Hale, Examples of Automated Genetic Analysis Developments. L. Rowen, S. Lasky and L. Hood, Deciphering Genomes Through Automated Large-scale Sequencing. N.C. Hauser, M. Scheideler, S. Matysiak, M. Vingron and J.D. Hoheisel, DNA Arrays for Transcriptional Profiling. K.-J. Reiger, G. Orlowska, A. Kaniak, J.-Y. Coppee, G. Alijinovic and P.P. Slonimski, Large-scale Phenotypic Analysis in Microtitre Plates of Mutants with Deleted Open Reading Frames From Yeast Chromosome III: Key-step Between Genomic Sequencing And Protein Function. J.J. Codani, J.P. Comet, J.C. Aude, E. Glémet, A. Wozniak, J.L. Risler, A. Hénaut and P.P. Slonimski, Automatic Analysis of Large-scale Pairwise Alignments of Protein Sequences. M.Y. Galperin and D. Frishman, Towards Automated Prediction of Protein Function from Microbial Genomic Sequences. Index.
Reviews
"Praise for the Volume ""The editors have complied an impressive group of international investigators and experts in microbial and genomic automation, producing a text that clearly describes the present and future importance of automated protocol in biomedical research. This text should be read by all biomedical researchers..."" --DOODY'S ELECTRONIC JOURNAL Praise for the Series ""An invaluable resource for the detailed analysis of cellular gene function and genome architecture."" --NATURE"
Praise for the Volume The editors have complied an impressive group of international investigators and experts in microbial and genomic automation, producing a text that clearly describes the present and future importance of automated protocol in biomedical research. This text should be read by all biomedical researchers... --DOODY'S ELECTRONIC JOURNAL Praise for the Series An invaluable resource for the detailed analysis of cellular gene function and genome architecture. --NATURE
Author Information
Jorg D. Hoheisel received his Ph.D. in 1988 from the University of Konstanz, Germany, where he studied DNA structures. He was at the ICRF in London, UK from 1988 to 1993, working on genome analysis. Since 1993, he has been Head at the DKFZ (Deutsches Krebsforschungzentrum) in Heidelberg, Germany.
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