Overview

Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other ""self"" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discusses possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their current limitations as unifying explanations of the diseases described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases.

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9781461272151

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Reviews

...tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other self systems.The authoritative expert writers explore the mechanistic aspects of...autoimmune diseases...and where possible, delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discuss possible general mechanisms of autoimmune disease...and their current limitations as unifying explanations of the disease described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases. -Journal of Investigational Allergology and Clinical Immunology

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