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Author:   Angela F. Drew
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2001 ed.
Volume:   52
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   1.230kg
ISBN:  

9780896037519

ISBN 10:   0896037517
Pages:   247
Publication Date:   31 October 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Animal Models of Diet-Induced Atherosclerosis.- Mechanical Injury Models.- Genetically Manipulated Models of Atherosclerosis in Mice.- Lipoprotein Isolation and Analysis from Serum by Preparative Ultracentrifugation.- Separation of Plasma Lipoproteins in Self-Generated Gradients of Iodixanol.- Fractionation of Lipoprotein Subclasses in Self-Generated Gradients of Iodixanol.- 7 Detecting Cholesteryl Ester Transfer Protein in Plasma.- 8 Determination of Plasma Homocysteine.- 9 Assay for Serum Glycated Lipoproteins.- 10 Lipoprotein(a) Quantitation.- Isolation and Characterization of Glycosaminoglycans from Human Atheromatous Vessels.- Culture of Human Smooth Muscle Cells.- Culture of Human Endothelial Cells.- Assay for Cell Migration and Invasion of Vascular Smooth Muscle Cells.- Collection and Processing of Arterial Specimens for Histological Analysis.- Intravascular Ultrasound Imaging in the Quantitation of Atherosclerosis in Vivo.- Identification of Cell Types and Quantification of Lesion Composition.- 1Nonradioactive In Situ Hybridization in Atherosclerotic Tissue.- Evaluation of Angiogenesis.- Evaluation of Cell Proliferation in Human Atherosclerotic Lesions.- Gene Transfer to the Vasculature Historical Perspective and Implications for Future Research Objectives.- A Pig Model of Vein Graft Disease Applications for Potential Gene Therapies.

Reviews

Methods for setting up animal model periments and special assays of blood and cellular moments of the pathologic processes involved are thoroughly described and referenced. Newly emerging animal models based on genetic manipulation are described in depth, with sufficient detail to broaden the scope of research by seasoned investigators to permit the novice to enter this field. ...Anyone working in vascular pathology and atherosclerosis research will find a wealth of practical information describing modern research methods. - Clinical and Applied Thrombosis/Hemostasis Atherosclerosis is recommended for academic health science libraries. It is also recommended to individual laboratories that conduct research in the area of atherosclerosis or heart disease. -E-STREAMS

"""Methods for setting up animal model periments and special assays of blood and cellular moments of the pathologic processes involved are thoroughly described and referenced. Newly emerging animal models based on genetic manipulation are described in depth, with sufficient detail to broaden the scope of research by seasoned investigators to permit the novice to enter this field. ...Anyone working in vascular pathology and atherosclerosis research will find a wealth of practical information describing modern research methods."" - Clinical and Applied Thrombosis/Hemostasis ""Atherosclerosis is recommended for academic health science libraries. It is also recommended to individual laboratories that conduct research in the area of atherosclerosis or heart disease."" -E-STREAMS"

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