Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

Author:   Allan Matte (Human Health Therapeutics, Research Center, National Research Council Canada, Montreal, QC, Canada)
Publisher:   Elsevier Health Sciences
ISBN:  

9780081030196


Pages:   222
Publication Date:   24 August 2020
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics


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Author:   Allan Matte (Human Health Therapeutics, Research Center, National Research Council Canada, Montreal, QC, Canada)
Publisher:   Elsevier Health Sciences
Imprint:   Elsevier / The Lancet
Weight:   0.540kg
ISBN:  

9780081030196


ISBN 10:   0081030193
Pages:   222
Publication Date:   24 August 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. LC-MS characterization of antibody-based therapeutics: recent highlights and future prospects 2. Engineering of Protein A for improved purification of antibodies and Fc-fused proteins 3. High fidelity affinity purification of Fc-fusion molecules from product related impurities 4. Recent advances in continuous downstream processing of antibodies and related products 5. Recent advances in antibody-based monolith chromatography for therapeutic applications 6. Recent advances in harvest clarification for antibodies and related products 7. Recent advances in ultrafiltration and virus filtration for production of antibodies and related biotherapeutics 8. A roadmap for IgG-like bispecific antibody purification 9. High-throughput, parallelized and automated protein purification for therapeutic antibody development

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Allan Matte is a Senior Research Officer in the Downstream Processing Team in HHT. With over 30 years of involvement in scientific R&D, he has coauthored more than 70 original research articles, reviews, and book chapters in various areas of protein science. He has also presented at a number of national and international conferences in the areas of high-throughput structural biology and antibody purification

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