Overview

"Filamentous fungi are a very large group of organisms, traditionally useful in the antibiotic, enzyme, chemical and food industries. More recently, their potential as hosts for the production of foreign proteins has been investigated, with mixed success. There is also a growing interest in the use of fungi for biological control. Written by an international team of authors, this book aims to provide a comprehensive overview of recent developments in the molecular biology of filamentous fungi and the application of these developments to a range of commercially useful fungi. Problems, successes and future prospects are examined. ""Destructive"" fungi, such as animal and plant pathogens, are not included. The book is directed at academic and industrial researchers in molecular biology, biotechnology, microbiology and genetics."

Full Product Details

Author:   J.R. Kinghorn ,  Geoffrey Turner
Publisher:   Chapman and Hall
Imprint:   Chapman and Hall
Edition:   1992 ed.
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   1.250kg
ISBN:  

9780751400588

ISBN 10:   0751400580
Pages:   259
Publication Date:   31 August 1992
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1 Fungal technology.- 1.1 Introduction.- 1.2 Selective markers.- 1.3 Transformation procedures.- 1.4 Fate of transforming DNA in Aspergillus nidulans.- 1.5 Expression vectors.- 1.6 Karyotyping.- 1.7 Restriction fragment length polymorphism mapping.- References.- 2 Gene organization in industrial filamentous fungi.- 2.1 Introduction.- 2.2 Gene structure.- 2.3 Gene regulation.- 2.4 Prospects.- References.- 3 Fungal enzymes used in oriental food and beverage industries.- 3.1 Introduction.- 3.2 Fungal industries in Japan.- 3.3 Fungal industries in China.- 3.4 Modern industries based on fungal enzymes.- 3.5 Genetic transformation systems for Rhizopus.- 3.6 Proteolytic enzymes.- 3.7 Pectinolytic enzymes and RNases.- 3.8 Lipases.- 3.9 Fungal enzymes used in starch processing.- 3.10 Summary.- References.- 4 Fungal enzymes for lignocellulose degradation.- 4.1 Introduction.- 4.2 Cellulose degradation.- 4.3 Hemicellulose degradation.- 4.4 Lignin degradation.- 4.5 Applications.- References.- 5 Foreign proteins.- 5.1 Introduction.- 5.2 Industrial enzymes and food products.- 5.3 Proteins of pharmaceutical interest.- 5.4 Expression of other proteins.- 5.5 Scale-up, production and regulatory aspects.- 5.6 Future prospects.- References.- 6 Stability of recombinant strains under fermentation conditions.- 6.1 Introduction.- 6.2 Fermentation.- 6.3 Isolation and stability of chymosin-producing strains.- 6.4 Regulatory issues.- 6.5 Preservation of recombinant fungal strains.- 6.6 Conclusions.- References.- 7 Molecular biology of filamentous fungi used for biological control.- 7.1 Introduction.- 7.2 Mechanisms of biological control activity.- 7.3 Strain improvement.- 7.4 Molecular markers for the characterization of biocontrol fungi.- References.- 8 The application of biotechnology to the button mushroom, Agaricus bisporus.- 8.1 Introduction.- 8.2 Biological barriers to mushroom strain development.- 8.3 Systematic isolation and verification of homokaryons.- 8.4 Production and verification of new mushroom strains.- 8.5 A genetic linkage map and karyotype analysis for the button mushroom.- 8.6 Molecular genetic studies on the mitochondria of Agaricus.- 8.7 Extrachromosomal elements in Agaricus.- 8.8 Conclusions.- References.- 9 The application of molecular genetics to oriental mushrooms.- 9.1 Introduction.- 9.2 Description of oriental edible fungi.- 9.3 Studies of the molecular biology and biochemistry of oriental mushrooms.- 9.4 Future prospects.- References.- 10 Secondary metabolites.- 10.1 Introduction.- 10.2 Fungal secondary metabolites.- 10.3 Are most genes for secondary metabolites tightly linked to each other?.- 10.4 Hybrid secondary metabolites: strains producing metabolites which are not formed in nature.- References.- 11 Future prospects.

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The editors have achieved much in bringing together a wide range of material in such an accessible form.TIBTech

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