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Overview"Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 & 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology. Volume 1 is divided into two sections: ""Malignant Transformation and Metastasis"" and ""Molecular Basis of Disease Therapy."" Volume 2 follows a similar structure and is divided into sections entitled ""Kinases and Phosphate"" and ""Molecular Basis of Cell Death."" All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases." Full Product DetailsAuthor: Rakesh SrivastavaPublisher: Humana Press Inc. Imprint: Humana Press Inc. Edition: Softcover reprint of hardcover 1st ed. 2007 Dimensions: Width: 17.80cm , Height: 2.10cm , Length: 25.40cm Weight: 0.881kg ISBN: 9781617378232ISBN 10: 1617378232 Pages: 402 Publication Date: 05 November 2010 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsKinases and Phosphatases.- Significance of Protein Kinase A in Cancer.- Protein Kinase C and Apoptosis.- The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infection.- Cyclin-Dependent Kinase 5.- Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistance.- MAPK Signaling in Human Diseases.- Serine/Threonine Protein Phosphatases in Apoptosis.- Urokinase/Urokinase Receptor-Mediated Signaling in Cancer.- Molecular Basis of Cell Death.- Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusion.- Cyclooxygenase-2 Gene Expression.- Death Receptors.- DNA Damage-Dependent Apoptosis.- The Role of Proteasome in Apoptosis.- Apoptosis Induction in T Lymphocytes by HIV.- Inhibitor of Apoptosis Proteins and Caspases.- Intracellular Pathways Involved in DNA Damage and Repair to Neuronal Apoptosis.- The Biology of Caspases.- Apoptosis and Human Diseases: Molecular Mechanisms.Reviews...an up-to-date synthesis of information regarding mechanisms of cell cycle control and apoptosis...filled with useful information and key references for readers familiar with this field. -Doody's Book Review, Weighted Numerical Score 77 - 3 stars ...provides a snapshot of current research as well as a vision of research opportunities and cancer therapies yet to come. -Doody's Book Review, Weighted Numerical Score 77 - 3 stars ...an up-to-date synthesis of information regarding mechanisms of cell cycle control and apoptosis...filled with useful information and key references for readers familiar with this field. -Doody's Book Review, Weighted Numerical Score 77 - 3 stars ...provides a snapshot of current research as well as a vision of research opportunities and cancer therapies yet to come. -Doody's Book Review, Weighted Numerical Score 77 - 3 stars Author InformationTab Content 6Author Website:Countries AvailableAll regions |