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OverviewA concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers: history of antifungals from the discovery of the polyenes to the echinocandins antifungal susceptibility methods patient management animal models in drug development therapeutic strategies pharmacokinetic and pharmacogenomics trends in resistance Full Product DetailsAuthor: Mahmoud A. Ghannoum, PhD, EMBA , John R. Perfect, MD , Mahmoud A Ghannoum , John PerfectPublisher: Taylor & Francis Inc Imprint: Informa Healthcare Dimensions: Width: 17.80cm , Height: 2.50cm , Length: 25.40cm Weight: 0.975kg ISBN: 9780849387876ISBN 10: 0849387876 Pages: 488 Publication Date: 01 November 2009 Audience: Professional and scholarly , Professional & Vocational , Professional & Vocational Replaced By: 9781498768146 Format: Hardback Publisher's Status: Out of Stock Indefinitely Availability: Out of stock ![]() Table of ContentsGeneral Introduction to the Management Issues History of Antifungals Ali Abdul Lattif and Kim Swindell Epidemiology of Fungal Infections: What, Where, and When Sylvia F. Costa and Barbara D. Alexander Experimental Animal Models of Invasive Fungal Infections Yoshifumi Imamura and Mahmoud A. Ghannoum Antifungal Drug Resistance: Significance and Mechanisms Pranab K. Mukherjee and Mingyue Wang Antifungal Prophylaxis: An Ounce of Prevention isWorth a Pound of Cure Aimee K. Zaas Preemptive Antifungal Therapy: Do Diagnostics Help? Kimberly E. Hanson The Immune Response to Fungal Challenge Jeffery J. Auletta Immunomodulators: What is the Evidence for Use in Mycoses? J. Andrew Alspaugh Fungal Biofilms and Catheter-Associated Infections Jyotsna Chandra and Mahmoud A. Ghannoum Antifungal Drug Classes Polyenes for Prevention and Treatment of Invasive Fungal Infections Richard H. Drew Flucytosine Richard H. Drew Pharmacology of Azole Antifungal Agents Elizabeth S. Dodds Ashley Echinocandins for Prevention and Treatment of Invasive Fungal Infections Melissa D. Johnson and John Mohr Novel Administrations of Antifungals Richard H. Drew Management of Specific Mycoses Dermatophytosis Susan A. Keiler and Mahmoud A. Ghannoum Invasive Candidiasis Rana Traboulsi and Mahmoud A. Ghannoum Invasive Aspergillosis Rana Traboulsi Management of Cryptococcosis John R. Perfect Management of Endemic Mycoses John R. Perfect Human Hyalohyphomycoses: A Review of Human Infections Due to Acremonium spp., Paecilomyces spp., Penicillium spp., and Scopulariopsis spp. Mahmoud A. Ghannoum Management of Phaeohyphomycosis John R. Perfect Pneumocystis Kim Swindell Management of Zygomycosis John R. Perfect The Paradigm of Risk Group/Infection Site Assessments Antifungal Management in Risk Groups: Transplant Recipients Sylvia F. Costa and Barbara D. Alexander Prophylaxis and Treatment of Invasive Fungal Infections in Neutropenic Cancer and Hematopoietic Stem Cell Transplant Patients Selmin A. Ataergin and Hillard M. Lazarus Infants: Yeasts Are Beasts in Early Life P. Brian Smith and Daniel K. Benjamin, Jr. Newer Antifungal Agents in Pediatrics Christina Henn and William J. Steinbach Fungal Infections in Burn Patients Jose A. Vazquez Allergic Bronchopulmonary Aspergillosis Rana Traboulsi Fungal Infections of the Genitourinary Tract Rana Traboulsi and Souha KanjReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |