Overview

Clinical issues.- Long-term course, comorbidity and long-term outcome in depressive disorders.- Do antidepressants really take several weeks to show effect?.- Commentary on the limitation of antidepressants in current use.- Mechanisms of action.- Mechanisms underlying the speed of onset of antidepressant response.- Calcium signaling cascades, antidepressants and major depressive disorders.- Markers of depression.- The hypothalamic-pituitary-adrenal axis and antidepressant action.- Neuroendocrine markers of depression and antidepressant drug action.- Brain cytokines and the psychopathology of depression.- The future of antidepressants.- Chemistry and pharmacology of novel antidepressants.

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9783764359331

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