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9781585282401

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Anticoagulation Therapy: A Point-of-Care Guideby William E. Dager, Michael P. Gulseth, Edith A. Nutescu. The Pharmaceutical Journal 17th September 2011 Vol 287/7671 page 325 The editors of this book have set out to create a unique, pocket-sized point-of-care practice guide that would give clinicians quick access to evidence-based information or expert opinion for challenging clinical situations. The book is designed to be light on text, heavy on tables and figures, easy to digest, comprehensive, expertly written, applicable to patients across the continuum of care and useful to all healthcare workers involved with these medicines. This is quite a challenge.The focus of the book is on the clinical use of anticoagulants. The information is organised according to the way that clinicians think through clinical problems.The book is divided into three parts: anticoagulant medicines management, conditions requiring anticoagulant therapy and practical monitoring, and coagulation laboratory insights.In the first part, several chapters are devoted to specific drug groups, including warfarin, unfractionated heparin, low molecular weight heparin, parenteral direct thrombin inhibitors and the newer oral anticoagulants. Although the chapter on the newer oral anticoagulants describes these agents as still being in development, the three drugs dabigatran, rivaroxaban and apixaban are compared and contrasted in great detail, with tables showing the results from the main published phase III clinical trials.In the second part, chapters deal with conditions requiring anticoagulant therapy, including atrial fibrillation, acute coronary syndromes and prosthetic heart valves. Other chapters cover pregnancy and paediatrics.A number of short miscellaneous appendices in diagrammatic or tabular format make up the final pages. Diverse subjects such as the coagulation cascade, cancer-related thromboembolism, drug related thrombocytopaenia and disseminated intravascular coagulation are covered.This excellent book has been written by authors who are experts in their fields of practice. It has met its objective in producing a useful guide for clinicians in any discipline caring for patients on anticoagulation therapy.Reviewer: Laurence A. Goldberg Laurence A. Goldberg is a pharmaceutical consultant in Bury, Lancashire --Laurence Goldberg The Pharmaceutical Journal (09/17/2011) **Description** This comprehensive guide to anticoagulants describes how they work, how they are used, clinical issues, and monitoring parameters and reversal guidelines. **Purpose** The purpose is to create a pocket guide that gives practitioners quick access to evidence-based and expert information on the use of anticoagulants in various types of patients. **Audience** The audience of clinical practitioners would include physicians in various specialties, including orthopedists, cardiologists, internists, general practitioners, residents, and medical students, as well as nurse practitioners, physician assistants, and pharmacists. **Features** The book discusses different anticoagulants, their mechanisms of action, dosing guidelines, monitoring parameters, and reversal guidelines. The clinical pearls are really helpful in addressing various situations such as dosing a morbidly obese patient. Many tables help make dosing comparisons, patient group comparisons, risk assessments, etc. Unfortunately, the font on some of the flow charts, diagrams, index, and back cover is very small and difficult to read. **Assessment** This is a wonderful little pocket guide to anticoagulation therapy. It is comprehensive, yet simplified. Updates will be needed as newer drug therapies come to market. ----------------------------------------------------------- Weighted Numerical Score: 84 - 3 Stars Judith Klevan, BA biology, BS Phamacy(Jeanes Hospital) --Judith Klevan, BA biology, BS Phamacy(Jeanes Hospital) MedInfoNow (06/03/2011)

Anticoagulation Therapy: A Point-of-Care Guide by William E. Dager, Michael P. Gulseth, Edith A. Nutescu. The Pharmaceutical Journal 17th September 2011 Vol 287/7671 page 325 <br>The editors of this book have set out to create a unique, pocket-sized point-of-care practice guide that would give clinicians quick access to evidence-based information or expert opinion for challenging clinical situations. The book is designed to be light on text, heavy on tables and figures, easy to digest, comprehensive, expertly written, applicable to patients across the continuum of care and useful to all healthcare workers involved with these medicines. This is quite a challenge.The focus of the book is on the clinical use of anticoagulants. The information is organised according to the way that clinicians think through clinical problems.The book is divided into three parts: anticoagulant medicines management, conditions requiring anticoagulant therapy and practical monitoring, and coagulation laboratory insights.In the first part, several chapters are devoted to specific drug groups, including warfarin, unfractionated heparin, low molecular weight heparin, parenteral direct thrombin inhibitors and the newer oral anticoagulants. Although the chapter on the newer oral anticoagulants describes these agents as still being in development, the three drugs dabigatran, rivaroxaban and apixaban are compared and contrasted in great detail, with tables showing the results from the main published phase III clinical trials.In the second part, chapters deal with conditions requiring anticoagulant therapy, including atrial fibrillation, acute coronary syndromes and prosthetic heart valves. Other chapters cover pregnancy and paediatrics.A number of short miscellaneous appendices in diagrammatic or tabular format make up the final pages. Diverse subjects such as the coagulation cascade, cancer-related thromboembolism, drug related thrombocytopaenia and disseminated intravascular coagulation arei

Anticoagulation Therapy: A Point-of-Care Guide by William E. Dager, Michael P. Gulseth, Edith A. Nutescu. The Pharmaceutical Journal 17th September 2011 Vol 287/7671 page 325 <br>The editors of this book have set out to create a unique, pocket-sized point-of-care practice guide that would give clinicians quick access to evidence-based information or expert opinion for challenging clinical situations. The book is designed to be light on text, heavy on tables and figures, easy to digest, comprehensive, expertly written, applicable to patients across the continuum of care and useful to all healthcare workers involved with these medicines. This is quite a challenge.The focus of the book is on the clinical use of anticoagulants. The information is organised according to the way that clinicians think through clinical problems.The book is divided into three parts: anticoagulant medicines management, conditions requiring anticoagulant therapy and practical monitoring, and coagulation labor

Anticoagulation Therapy: A Point-of-Care Guideby William E. Dager, Michael P. Gulseth, Edith A. Nutescu. The Pharmaceutical Journal 17th September 2011 Vol 287/7671 page 325 The editors of this book have set out to create a unique, pocket-sized point-of-care practice guide that would give clinicians quick access to evidence-based information or expert opinion for challenging clinical situations. The book is designed to be light on text, heavy on tables and figures, easy to digest, comprehensive, expertly written, applicable to patients across the continuum of care and useful to all healthcare workers involved with these medicines. This is quite a challenge.The focus of the book is on the clinical use of anticoagulants. The information is organised according to the way that clinicians think through clinical problems.The book is divided into three parts: anticoagulant medicines management, conditions requiring anticoagulant therapy and practical monitoring, and coagulation laboratory insights.In the first part, several chapters are devoted to specific drug groups, including warfarin, unfractionated heparin, low molecular weight heparin, parenteral direct thrombin inhibitors and the newer oral anticoagulants. Although the chapter on the newer oral anticoagulants describes these agents as still being in development, the three drugs dabigatran, rivaroxaban and apixaban are compared and contrasted in great detail, with tables showing the results from the main published phase III clinical trials.In the second part, chapters deal with conditions requiring anticoagulant therapy, including atrial fibrillation, acute coronary syndromes and prosthetic heart valves. Other chapters cover pregnancy and paediatrics.A number of short miscellaneous appendices in diagrammatic or tabular format make up the final pages. Diverse subjects such as the coagulation cascade, cancer-related thromboembolism, drug related thrombocytopaenia and disseminated intravascular coagulation are covered.This excellent book has been written by authors who are experts in their fields of practice. It has met its objective in producing a useful guide for clinicians in any discipline caring for patients on anticoagulation therapy.Reviewer: Laurence A. Goldberg Laurence A. Goldberg is a pharmaceutical consultant in Bury, Lancashire --Laurence Goldberg The Pharmaceutical Journal (09/17/2011) **Description**This comprehensive guide to anticoagulants describes how they work, how they areused, clinical issues, and monitoring parameters and reversal guidelines. **Purpose**The purpose is to create a pocket guide that gives practitioners quick access toevidence-based and expert information on the use of anticoagulants in varioustypes of patients. **Audience**The audience of clinical practitioners would include physicians in variousspecialties, including orthopedists, cardiologists, internists, generalpractitioners, residents, and medical students, as well as nurse practitioners, physician assistants, and pharmacists. **Features**The book discusses different anticoagulants, their mechanisms of action, dosingguidelines, monitoring parameters, and reversal guidelines. The clinical pearlsare really helpful in addressing various situations such as dosing a morbidlyobese patient. Many tables help make dosing comparisons, patient groupcomparisons, risk assessments, etc. Unfortunately, the font on some of the flowcharts, diagrams, index, and back cover is very small and difficult to read. **Assessment**This is a wonderful little pocket guide to anticoagulation therapy. It iscomprehensive, yet simplified. Updates will be needed as newer drug therapiescome to market. ----------------------------------------------------------- Weighted Numerical Score: 84 - 3 Stars Judith Klevan, BA biology, BS Phamacy(Jeanes Hospital) --Judith Klevan, BA biology, BS Phamacy(Jeanes Hospital) MedInfoNow (06/03/2011)

Anticoagulation Therapy: A Point-of-Care Guide by William E. Dager, Michael P. Gulseth, Edith A. Nutescu. The Pharmaceutical Journal 17th September 2011 Vol 287/7671 page 325 The editors of this book have set out to create a unique, pocket-sized point-of-care practice guide that would give clinicians quick access to evidence-based information or expert opinion for challenging clinical situations. The book is designed to be light on text, heavy on tables and figures, easy to digest, comprehensive, expertly written, applicable to patients across the continuum of care and useful to all healthcare workers involved with these medicines. This is quite a challenge.The focus of the book is on the clinical use of anticoagulants. The information is organised according to the way that clinicians think through clinical problems.The book is divided into three parts: anticoagulant medicines management, conditions requiring anticoagulant therapy and practical monitoring, and coagulation laboratory insights.In the first part, several chapters are devoted to specific drug groups, including warfarin, unfractionated heparin, low molecular weight heparin, parenteral direct thrombin inhibitors and the newer oral anticoagulants. Although the chapter on the newer oral anticoagulants describes these agents as still being in development, the three drugs dabigatran, rivaroxaban and apixaban are compared and contrasted in great detail, with tables showing the results from the main published phase III clinical trials.In the second part, chapters deal with conditions requiring anticoagulant therapy, including atrial fibrillation, acute coronary syndromes and prosthetic heart valves. Other chapters cover pregnancy and paediatrics.A number of short miscellaneous appendices in diagrammatic or tabular format make up the final pages. Diverse subjects such as the coagulation cascade, cancer-related thromboembolism, drug related thrombocytopaenia and disseminated intravascular coagulation aret

Author Information

William E. Dager, Pharm.D., FCSHP, FCCP, is Clinical Professor of Pharmacy at the University of California, San Francisco (UCSF) School of Pharmacy and Clinical Professor of Medicine at University of California, Davis School of Medicine, USA. Dr. Dager received his doctor of pharmacy degree from UCSF and served a residency at the University of California, Davis Medical Center (UCDMC) in Sacramento. He also completed a preceptorship in nephrology/pharmaceutical care at the University of Pittsburgh School of Pharmacy. In his role as a clinical specialist at UCDMC, Dr. Dager is responsible for managing difficult cases in anticoagulation, pharmacokinetics, and critical care. Dr. Dager is a fellow of the California Society of Health-System Pharmacists (CSHP) and was recently recognized as a fellow of the American College of Clinical Pharmacy (ACCP). In October 2008, Dr. Dager was honored with the ACCP Clinical Practice Award in recognition of his outstanding contributions in the area of clinical pharmacy practice. Dr. Dager is a member of numerous professional organizations, including the Sacramento Valley Society of Heath-System Pharmacists, the Anticoagulation Forum, the International Society of Thrombosis and Haemostasis, the American Society of Health-System Pharmacists (ASHP), and the American College of Clinical Pharmacy. Dr. Dager currently serves as an instructor and regional affiliate faculty in advanced cardiac life support (ACLS) for the American Heart Association. Dr. Dager serves as a reviewer and editorial board member for several medical journals. He is currently chairman of the Editorial Advisory Board Panel on Anticoagulation for Annals of Pharmacotherapy. He is also a 2008 site coordinator for the ASHP Foundation's anticoagulation preceptorship. Dr. Dager has authored numerous articles, book chapters, and scientific reviews and has presented at national and international educational conferences. He is the recipient of multiple teaching awards, is an active lecturer; and is involved in several research projects in the areas of anticoagulation, critical care medicine, cardiovascular disease, pharmacokinetics, and pharmacodynamics. Michael P. Gulseth, Pharm.D., BCPS, is Program Director for Anticoagulation Services at the Sanford University of South Dakota Medical Center, Department of Pharmaceutical Services in Sioux Falls, South Dakota, USA. Dr. Gulseth received his Doctor of Pharmacy degree in 1999 from North Dakota State University in Fargo, North Dakota. He completed residency training at United Hospital in St. Paul, Minnesota. He is lead author and editor of Managing Anticoagulation Patients in the Hospital: the Inpatient Anticoagulation Service, published in 2007 by the American Society of Health-System Pharmacists. Dr. Gulseth is a member of the Editorial Advisory Board of the American Journal of Health-System Pharmacy. Dr. Gulseth is an active member of several professional pharmacy organizations, including the American Society of Health- System Pharmacists, the Minnesota Society of Health-System Pharmacists, the South Dakota Society of Health-System Pharmacists, and the American College of Clinical Pharmacy. His research interests include evaluation of antithrombotic therapies in the inpatient setting and evaluation of the benefits of pharmacist managed inpatient anticoagulation services. Edith A. Nutescu, Pharm.D., FCCP,, is Clinical Professor in the Department of Pharmacy Practice and Center for Pharmacoeconomic Research at the University of Illinois at Chicago College of Pharmacy, USA. She also serves as the Clinical Manager of the Antithrombosis Center at the University of Illinois at Chicago Medical Center. Dr. Nutescu earned her Pharm.D. degree with high honors at the University of Illinois at Chicago College of Pharmacy. After graduation, Dr Nutescu went on to complete an American Society of Health-System Pharmacists (ASHP) - accredited Pharmacy Practice Residency at Lutheran General Hospital - Advocate Health Care and a Primary Care Specialty Residency at the University of Illinois at Chicago Medical Center. As a clinician and educator, Dr. Nutescu has contributed extensively to the care of patients and the education of students and health care providers on topics related to cardiovascular therapeutics. Dr. Nutescu maintains an active clinical practice and research program. Her research and practice interests are in the areas of comparative effectiveness, health services and outcomes, with emphasis in cardiovascular diseases, stroke, thrombosis, and antithrombotic therapies. Dr Nutescu has authored or co-authored over 100 scientific articles, book chapters, and abstracts published in the science and medical literature and has served as a reviewer for the literature in her field. Dr. Nutescu's research has been funded by the Department of Health and Human Services and the National Center for Research Resources and is a recipient of the Ruth L. Kirchstein National Research Service Award for 2009-2011. Dr. Nutescu is the recipient of the American College of Clinical Pharmacy's 2009 Clinical Practice Award and the American Society of Health System Pharmacists, Section of Home and Ambulatory Care Practitioners 2010 Distinguished Service Award.

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