Overview

Providing information on physiological anticoagulants, this text covers the tissue factor pathway inhibitor, and how changes in these proteins promote thrombosis. Details of recommended treatment are included, informing the reader on the appropriate use of current medications, their advantages and pitfalls. The text provides detailed clinical advice for the management of patients with congenital clotting factor deficiencies and patients who were previously well. It includes research on tissue factor pathway inhibitors, low molecular weight heparin, activated Factor VII and lupus coagulants. Guidelines for the use of heparin, wafarin and thrombolytic agents are also provided.

Full Product Details

Author:   David Green
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Weight:   0.590kg
ISBN:  

9780849347627

ISBN 10:   0849347629
Pages:   288
Publication Date:   06 June 1994
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Physiologic Inhibitors: Clinical and Physiological Manifestations of the Protein C Anticoagulant Pathway (C.T. Esmon). Protein S: Clinical and Laboratory Aspects (P.C. Comp). Antithrombin III (M. Manco-Johnson). Tissue Factor Pathway Inhibitor-A Regulator of Tissue Factor Induced Coagulation (M.S. Bajaj, A. Ameri, and S.P. Bajaj). Pathologic Inhibitors: Overview of Factor VIII Inhibitors (J.A. Penner). Immune Tolerance: Historical Perspective and Future Direction (D.M. DiMichele). Inhibitors of Factor VIII in Non-Hemophiliacs (D. Green). The Treatment of Acquired Hemophilia with Porcine Factor VIII Concentrate (C.M. Kessler). Use of Factor IX Complex Concentrates (Prothrombin Complex Concentrates) in Hemophiliacs with Inhibitor Antibodies to Factor VIII or Factor IX (J.M. Lusher). Pathologic Inhibitors (S. Glazer, U. Hedner, J.F. Falch). Lupus Anticoagulants (J.R. Chediak). Acquired von Willebrand's Disease (G.A. Soff). Acquired Inhibitors of Fibrin Stabilization: A Class of Hemorrhagic Disorders of Diverse Origins (L. Lorand). Pharmacologic Inhibitors: Heparin Therapy: Recent Advances in the Treatment of Venous and Arterial Thrombosis (G.F. Pineo, G.E. Raskob, and R.D. Hull). Warfarin Therapy (G.E. Raskob, P.C. Comp, G.F. Pineo, and R.D. Hull). Low Molecular Weight Heparins in the Management of Thrombotic Disorders (J. Fareed, D. Hoppensteadt, J.M. Walenga, W. Jeske, and A. Ahsan). Thrombolytic Therapy-Old and New (H.C. Kwaan).

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