Overview

Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This work describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.

Full Product Details

Author:   Dennis R. Burton
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   2001 ed.
Volume:   260
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   1.400kg
ISBN:  

9783540416111

ISBN 10:   3540416110
Pages:   309
Publication Date:   06 June 2001
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

List of Contents.- Antibody Interactions with Rhinovirus: Lessons for Mechanisms of Neutralizationand the Role of Immunity in Viral Evolution.- Structural Studies on Antibody Interacting with Viruses.- Shape and Electrostatic Complementarity at Viral Antigen-Antibody Complexes.- Structural Studies on Viral Escape from Antibody Neutralization.- Affinity, Complementarity, Cooperativity, and Specificity in Antibody Recognition.- Mechanisms of Virus Neutralization by Antibody.- A Model for Neutralization of Viruses Based on Antibody Coating of the Virion Surface.- Antibody-Mediated Enhancement of Viral Disease.- The Role of the Antibody Response in Influenza Virus Infection.- Role of Antibodies in Controlling Alphavirus Infection of Neurons.- Role of Mucosal Antibodies in Viral Infections.- The Role of the Complement System in Virus Infections.- Intrabodies as Antiviral Agents.- T-Bodies as Antiviral Agents.

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