Overview

The Fifth Edition of this highly acclaimed reference describes state-of-the-art laboratory methods for evaluating the efficacy of antibiotics and the mechanisms of bacterial resistance. Coverage includes new molecular techniques for antibiotic testing, the new discipline of pharmacogenomics, and use of computers to monitor resistance trends. New chapters focus on the breakpoint, molecular techniques for susceptibility testing, susceptibility testing of HIV and hepatitis agents to antiviral drugs, and disinfectant and antiseptic testing. Sixteen new antimicrobial agentsumost FDA-approved, others German and UK-approveduare examined. More than 200 tables provide information on every organism, every antimicrobial agent, and drug concentrations in blood, organs, and tissues.

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