Overview

Combinatorial chemistry and molecular diversity approaches to scientific and novel product research and development have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications.

Full Product Details

Author:   M.R. Pavia ,  W.H. Moos
Publisher:   Springer
Imprint:   Springer
Edition:   Partly reprinted from MOLECULAR DIVERSITY, 3/4, 1999
Volume:   2
Dimensions:   Width: 21.00cm , Height: 1.20cm , Length: 27.90cm
Weight:   1.260kg
ISBN:  

9780792357223

ISBN 10:   0792357221
Pages:   174
Publication Date:   30 June 1999
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Solution-phase combinatorial chemistry.- New developments in solid phase synthesis supports.- Recent advances in solid phase synthesis.- Purification of combinatorial libraries.- Analytical methods for quality control of combinatorial libraries.- Accessing carbohydrate-based combinatorial libraries through solid phase and solution phase approaches.- Patent strategies in molecular diversity.- Patent tactics in molecular diversity: Things that get around, come around (Or: There are always exceptions to the rule).- Advances in diversity profiling and combinatorial series design.- Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997.- A compendium of solid-phase chemistry publications.- Author Index.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions