Overview

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development.; Nevertheless, attrition rates in clinical development are still very high, and up to 90 per cent of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy.; This indicates a strong need for highly predictive in vitro and in vivo models.; The 50th International Workshop of the Ernst Schering Research Foundation focussed on Animal Models of T Cell-Mediated Skin Diseases. ; Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.; The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

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9786610745579

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