Overview

Animal Models of Neurological Conditions informs about novel animal models and their unique strengths and limitations in the research of neurological conditions. It demonstrates the importance of animal models’ abilities to replicate only aspects of a given neurological condition and highlights the value of these animal models in increasing human brain function in afflicted patients. This book, comprised of thirteen chapters discusses various animal models and research methods for mental health, neurodevelopmental disorders, addiction, age-related neurodegenerative conditions, and viruses affecting brain function. Although developed with neuroscience researchers and trainees involved in pre-clinical and clinical research in mind, neurologists and other treatment professionals caring for patients with neurological conditions will also find value in this detailed resource. This is an invaluable resource for neuroscience researchers, trainees, and healthcare professionals.

Full Product Details

Author:   Jacob Raber (Professor of Behavioral Neuroscience, School of Medicine, Oregon Health and Science University and Principal Investigator, Oregon National Primate Research Center, Beaverton, Oregon, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780443290909

ISBN 10:   0443290903
Pages:   502
Publication Date:   09 December 2025
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Section 1: Animal model of mental health 1. Animal models of depression 2. Animal models of hydrocephalus 3. Animal models of autism 4. Posttraumatic stress disorder animal models and anxiety disorders Section 2: Animal models of neurodevelopmental disorders 5. Animal models of ADHD 6. Animal models of developmental brain disorders Section 3: Animal models of addiction 7. Animal models of alcohol and drugs of abuse Section 4: Animal models of age-related neurodegenerative conditions 8. Novel mouse models to assess brain function 9. Parkinson’s disease animal models 10. Alzheimer’s disease mouse models 11. Multiple sclerosis animal models 12. Animal models of mild cognitive impairment 13. Animal models of traumatic brain injury 14. Animal models of ischemic and vascular conditions 15. Animal models of vision-related neurological conditions 16. Animal models of hearing-related neurological conditions 17. Animal models of the blood-brain barrier function 18. Animal model of anesthesia-induced cognitive injury Section 5: Animal models of cancer and cancer treatments 19. Mouse models of pancreatic cancers and cancer treatments affecting the brain Section 6: Animal models of metabolic conditions 20. Mouse models of Phenylketonuria Section 7: Animal models of viruses affecting brain function 21. Animal models of neurotropic viruses 22. Animal models of bird flu 23. Animal models of zika virus

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Author Information

Jacob Raber, PhD received his BS in Chemistry and MS in Pharmacochemistry from the Free University of Amsterdam, his PhD in Molecular Genetics and Virology from the Weizmann Institute of Science, and further training under Floyd Bloom at the Scripps Research Institute, La Jolla, and Lennart Mucke at the Gladstone Institutes and UCSF. In 2001 he was recruited to Oregon Health & Science University (OHSU) in Portland, Oregon and currently serves as a professor in the Departments of Behavioral Neuroscience, Neurology, Psychiatry, and Radiation Medicine, an affiliate scientist in the division of Neuroscience at the ONPRC, and a Courtesy Professor in the College of Pharmacy at Oregon State University. He was an Ellison Medical Foundation New Scholar in Aging from 2002-2006. Dr Raber’s research is devoted to characterizing effects of environmental and genetic factors on brain function, identifying of affected pathways, and developing treatments to antagonize detrimental effects.

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