Overview

Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.Page and F. Merlin Bumpus expanded the Handbook of Experimental Pharmacology. Even after two decades the multiplicity of its actions appears not to have been fully discovered. To call attention to its many functions is one of the purposes of this book. This new edition of the volume on Angiotensin attempts to provide an updated account of the knowledge and findings accumulated since the complexity of angiotensin was so accurately recognized.

Full Product Details

Author:   Thomas Unger ,  Bernward A. Schölkens
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2004
Volume:   163 / 2
Dimensions:   Width: 15.50cm , Height: 3.20cm , Length: 23.50cm
Weight:   0.937kg
ISBN:  

9783642621338

ISBN 10:   3642621333
Pages:   603
Publication Date:   03 October 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

List of Contents.- 4. Tissues.- Vascular.- Angiotensin II and Oxidative Stress.- Angiotensin II and Atherosclerosis.- Angiotensin II and Vascular Extracellular Matrix.- Renin-Angiotensin Inhibitors and Vascular Effects.- Brain/Nervous System.- Angiotensin Pathways and Brain Function.- Involvement of the Renin Angiotensin System in the Regulation of the Hypothalamic Pituitary Adrenal Axis.- Angiotensin Actions on the Brain Influencing Salt and Water Balance.- Angiotensin Receptor Signaling in the Brain: Ionic Currents and Neuronal Activity.- Angiotensin, Neuroplasticity and Stroke.- Heart.- Role of Angiotensin II in Cardiac Remodeling.- Pathophysiology of Cardiac AT1 and AT2 Receptors.- Activation of the Renin-Angiotensin System After Myocardial Infarction.- Kidney and Adrenal Gland.- Angiotensin II, the Kidney and Hypertension.- Angiotensin and Aldosterone Biosynthesis.- Aldosterone: Clinical Aspects.- 5. Inhibition of the Renin-Angiotensin System.- ACE Inhibitors.- Interactions Between the Renin-Angiotensin and the Kallikrein-Kinin System.- ACE Inhibitors: Pharmacology.- AT1 Antagonists.- AT1 Receptor Antagonists: Pharmacology.- Clinical Pharmacology of Angiotensin II Receptor Antagonists.- Combined Blockade of the Renin Angiotensin System with ACE Inhibitors and AT1 Receptor Antagonists.- NEP/ACE Inhibitors.- NEP/ACE Inhibitors: Experimental and Clinical Aspects.- 6. Clinical Qutlook.- Inhibitors of the RAS: Evidence-Based Medicine.

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