Overview

Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.Page and F. Merlin Bumpus expanded the Handbook of Experimental Pharmacology. Even after two decades the multiplicity of its actions appears not to have been fully discovered. To call attention to its many functions is one of the purposes of this book. This new edition of the volume on Angiotensin attempts to provide an updated account of the knowledge and findings accumulated since the complexity of angiotensin was so accurately recognized.

Full Product Details

Author:   Thomas Unger ,  Bernward A. Schölkens
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2004
Volume:   163 / 1
Dimensions:   Width: 15.50cm , Height: 2.90cm , Length: 23.50cm
Weight:   0.860kg
ISBN:  

9783642621321

ISBN 10:   3642621325
Pages:   548
Publication Date:   03 October 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

List of Contents.- 1. General Aspects.- General Physiology and Pathophysiology of the Renin-Angiotensin System.- Phylogeny and Ontogeny of the Renin-Angiotensin System.- Angiotensin as a Cytokine Implicated in Accelerated Cellular Turnover.- Regulation of Angiogenesis by Angiotensin II.- Immunohistochemistry of Angiotensin.- Renin-Angiotensin System: Plasma Versus Tissues.- Angiotensin-Endothelin Interactions.- 2. Genetics.- Genetics of the Human Renin-Angiotensin System.- Knockout Models of the Renin-Angiotensin System.- Transgenics of the RAS.- Gene Therapy and the Renin-Angiotensin System.- 3. ANG Receptors.- AT1.- AT1 Receptor Molecular Aspects.- AT1 Receptor Interactions.- AT1 Receptor Regulation.- Angiotensin AT1 Receptor Signal Transduction.- Sympathetic Interactions of AT1 Receptors.- AT2.- Molecular Aspects of AT2 Receptor.- AT2 Receptor of Angiotensin II and Cellular Differentiation.- AT2 Renal Aspects.- AT2 Function and Target Genes.- Angiotensin-(1-7). Its Contribution to Arterial Pressure Control Mechanisms.- Angiotensin AT4 Receptor.

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