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Angiogenesis: In Vitro Systems

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Author:   David A. Cheresh (The Scripps Research Institute, La Jolla, CA, USA) ,  David A. Cheresh (The Scripps Research Institute, La Jolla, CA, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   443
Dimensions:   Width: 15.20cm , Height: 2.50cm , Length: 22.90cm
Weight:   0.780kg
ISBN:  

9780123743152

ISBN 10:   012374315
Pages:   432
Publication Date:   14 October 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Studying cell signaling pathways; Flow mediated signaling; Endothelial cell adhesion and migration on the ECM; EC sprouting assays; Lumen formation assays; Isolation and propagation of EC's or SMC's; Cell-based assays to screen anti-angiogenic agents (chemical approach; ES cell models of vascular network formation; Co-culture studies with EC plus other cell types; Aortic ring sprouting (multiple cell types present); Effects of hypoxia or hyperoxia; Vascular Proteomics; In vitro vascular barrier function; EC leukocyte interactions; ECM signaling to the vasculature; Vascular Integrin signaling; Mechanical Signaling in blood vessels; Vascular and neuronal patterning; Vascular growth factors and their signals; VEGF receptor signal transduction; Development and testing of monoclonal antibodies directed to angiogenic targets.

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