Overview

This is a comprehensive analysis of androgens and androgen receptor, including discussions of the basic mechanisms of androgen-androgen receptor actions, their roles in the androgen-related diseases, and their potential clinical applications. This book covers key topics including: the discovery and cloning of the androgen receptor; androgen receptor co regulators; androgen related genes and their consensus DNA response elements and the basic mechanism of action including functional analyses, cellular localization and phosphorylation studies. It explores the cross-talk to other signal transduction systems and the recent connections of androgens to women's diseases, such as osteoporosis and ovarian cancer. This book could be of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.

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9781402071881

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Author Information

Chawnshang Chang, Ph.D., is the George Hoyt Whipple Distinguished Professor at the University of Rochester.

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