Androgen Action: Methods and Protocols

Author:   Fahri Saatcioglu
Publisher:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 2011
Volume:   776
ISBN:  

9781493962013


Pages:   389
Publication Date:   23 August 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Androgen Action: Methods and Protocols


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Author:   Fahri Saatcioglu
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 2011
Volume:   776
Weight:   1.028kg
ISBN:  

9781493962013


ISBN 10:   1493962019
Pages:   389
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Molecular Mechanisms of Androgen Action – A Historical Perspective.- Androgen Action during Prostate Carcinogenesis.- Androgen Quantitation in Prostate Cancer Tissue using Liquid Chromatography Tandem Mass Spectrometry.- Ligand Competition Binding Assay for the Androgen Receptor.- Analysis of Androgen Receptor Activity by Reporter Gene Assays.- Identification and Characterization of Androgen Response Elements.- In vitro and In vivo Silencing of the Androgen Receptor.- Analysis of Interdomain Interactions of the Androgen Receptor.- Methods to Study Dynamic Interaction of Androgen Receptor with Chromatin in Living Cells.- FRET Analysis of Androgen Receptor Structure and Biochemistry in Living Cells.- Analysis of Nuclear Receptor Acetylation.- Analysis of Androgen Receptor SUMOylation.- Analysis of Ligand-specific Co-repressor Binding to the Androgen Receptor.- Detection of Ligand-selective Interactions of the Human Androgen Receptor by SELDI-MS-TOF.- Global Identification of Androgen Response Elements.- Tissue Specific Knockout of Androgen Receptor in Mice.- Methodology to Investigate Androgen-sensitive and Castration-resistant Human Prostate Cancer Xenografts in Preclinical Setting.- Automated Microscopy and Image Analysis for Androgen Receptor Function.- Androgen Regulation of ETS-gene Fusion Transcripts in Prostate Cancer.- Regulation of Apoptosis by Androgens in Prostate Cancer Cells.- Analysis of Androgen Receptor Rapid Actions in Cellular Signaling Pathways: Receptor /Src Association.- Analysis of Androgen-induced Increase in Lipid Accumulation in Prostate Cancer Cells.

Reviews

From the reviews: The Editor asked more than 50 experts from three continents and put them together to contribute with their up-to-date written chapters. This valuable volume begins with two chapters on the history of androgen research, especially with androgen action and prostate carcinogenesis. ... This volume will certainly provide the reader with a comprehensive overview of, and practical guidance on, the discrete methodologies which are propelling androgen research forward. (Endocrine Regulations, October, 2012) This book details protocols to determine androgen levels, actions mediated by AR, and cross-talk with other key signaling networks. ... The techniques are most appropriate for biochemists and molecular and cellular biologists who are engaged in the study of androgen-mediated events. ... This effectively written and thought-out book will serve as useful resource to decipher the complex actions of androgens. ... The compilation of knowledge and wisdom in this book will be beneficial to current and future researchers. (Clay E. S. Comstock, Doody's Book Reviews, February, 2012)


From the reviews: “The Editor asked more than 50 experts from three continents and put them together to contribute with their up-to-date written chapters. This valuable volume begins with two chapters on the history of androgen research, especially with androgen action and prostate carcinogenesis. … This volume will certainly provide the reader with a comprehensive overview of, and practical guidance on, the discrete methodologies which are propelling androgen research forward.” (Endocrine Regulations, October, 2012) “This book details protocols to determine androgen levels, actions mediated by AR, and cross-talk with other key signaling networks. … The techniques are most appropriate for biochemists and molecular and cellular biologists who are engaged in the study of androgen-mediated events. … This effectively written and thought-out book will serve as useful resource to decipher the complex actions of androgens. … The compilation of knowledge and wisdom in this book will be beneficial to current and future researchers.” (Clay E. S. Comstock, Doody’s Book Reviews, February, 2012)


From the reviews: The Editor asked more than 50 experts from three continents and put them together to contribute with their up-to-date written chapters. This valuable volume begins with two chapters on the history of androgen research, especially with androgen action and prostate carcinogenesis. ... This volume will certainly provide the reader with a comprehensive overview of, and practical guidance on, the discrete methodologies which are propelling androgen research forward. (Endocrine Regulations, October, 2012) This book details protocols to determine androgen levels, actions mediated by AR, and cross-talk with other key signaling networks. ... The techniques are most appropriate for biochemists and molecular and cellular biologists who are engaged in the study of androgen-mediated events. ... This effectively written and thought-out book will serve as useful resource to decipher the complex actions of androgens. ... The compilation of knowledge and wisdom in this book will be beneficial to current and future researchers. (Clay E. S. Comstock, Doody's Book Reviews, February, 2012)


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