Overview

Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.

Full Product Details

Author:   Mariana C. Castells
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   0.903kg
ISBN:  

9781603279505

ISBN 10:   1603279504
Pages:   361
Publication Date:   10 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface.- Foreword.- Definition and Criteria for the Diagnoses of Anaphylaxis.- An Epidemiological Approach to Reducing the Risk of Fatal Anaphylaxis.- Pathophysiology and Organ Damage in Anaphylaxis.- Mast Cells: Effector Cells of Anaphylaxis.- Basophils in Anaphylaxis.- Protease Mediators of Anaphylaxis.- Aspirin and NSAID Reactions: Diagnosis, Pathophysiology, and Management.- IgE-dependent and Independent Effector Mechanisms in Human and Murine Anaphylaxis.- Food-Induced Anaphylaxis.- Antibiotic-induced Anaphylaxis.- Anaphylaxis During Radiological Procedures and in the Peri-operative Setting.- Hymenoptera-induced Hypersensitivity Reactions and Anaphylaxis.- Idiopathic Anaphylaxis.- xercise-induced Anaphylaxis and Food-dependent Exercise-induced Anaphylaxis.- Mastocytosis and Mast Cell Activation Syndromes Presenting as Anaphylaxis.- Anaphylaxis in Mastocytosis.- Flushing and Urticarial Syndromes Presenting as Anaphylaxis.- Pharmacologic Management of Acute Anaphylaxis.- Drug Desensitizations in the Management of Allergy and Anaphylaxis to Chemotherapeutic Agents and Monoclonal Antibodies.- Rapid Desensitizations for Antibiotic-induced Hypersensitivity Reactions and Anaphylaxis.- Induction of Tolerance for Food-induced Anaphylaxis.- Management of Anaphylaxis: Relevance of Causes and Future Trends in Treatment

Reviews

From the reviews: Presents a detailed look at the current state of knowledge on anaphylaxis and hypersensitivity reactions. achieves its objectives in a very readable fashion. The book is meant for clinicians of all types, translational researchers, and basic researchers. useful for a graduate level course. quite readable and one could go through the book from cover to cover without losing interest. packed with useful information about anaphylaxis and hypersensitivity reactions. The material is presented in a clear and readable fashion by experts. (Marion C. Cohen, Doody 's Review Service, June, 2011)

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